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Novel ‘Global Shear Vector’ Metric Provides New Insights Into Spinal Alignment

Tool correlates well with sagittal vertical axis and quality-of-life measures

illustration of an alzheimer brain and a packet of sildenafil pills
March 11, 2024/Neurosciences/Research

Sildenafil as an Alzheimer’s Candidate Drug: Further Support From Insurance Database and Mechanistic Studies

Real-world claims data and tissue culture studies set the stage for randomized clinical testing

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Multi-Ancestry Genetic Study of Parkinson’s Disease Identifies New Risk Genes in Pursuit of Novel Treatment Targets

International collaboration is most genetically diverse study of the disease to date

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Noninvasive Technology Enhances Ability to Map Brain Activity to Track Behavior Change

Preclinical work promises large-scale data with minimal bias to inform development of clinical tests

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December 11, 2023/Behavioral Health

American Psychiatrists Reveal Changing Attitudes About the Therapeutic Use of Classic Hallucinogens

Study shows a growing openness to the clinical potential of psychedelic treatments

Feixiong Cheng, MD

An All-Fronts Approach to Understanding and Overcoming Alzheimer’s Disease

A conversation with Feixiong Cheng, PhD, about his wide-ranging research initiatives

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October 27, 2023/Behavioral Health

75 Years Later: Cleveland Clinic Recalls Researchers’ Pivotal Role in Discovery of Serotonin

Finding changes the treatment landscape of psychiatric illness

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Advanced Computational and Imaging Tools Yield Insights Into Learning and Decision-Making

Research aims to extend observations of reversal learning in mice to human neurological disorders

Brain scans

Does Sleep Dysfunction Help Explain Sex Differences in Alzheimer’s Incidence and Progression?

Novel research is comparing sleep measures to biomarkers of neurodegeneration

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TREM2 Deficiency Hinders Recovery and Phagocytosis in Virus-Induced Demyelination

Model of viral encephalomyelitis shows links with CNS recovery from inflammation and damage

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