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Research

Man on an exercise bicycle
October 29, 2024/Neurosciences/Research

New Parkinson’s Trial Focuses on Interplay Between Exercise and Genetics

Study aims to inform an enhanced approach to exercise as medicine

researcher in dark laboratory
September 12, 2024/Neurosciences/Research

Preclinical Imaging Research Aims to Help Refine Deep Brain Stimulation for Stroke Recovery

$3.2 million grant will fund use of calcium-based imaging to record neuronal activity in ischemia model

neurons, axons and synapses in the brain
September 5, 2024/Neurosciences/Research

A Case Study in Neurotherapeutic Clinical Trial Design and Conduct

New phase 1 trial showcases Neurological Institute’s interdisciplinary study capabilities

anatomic spine with vectors displayed

Novel ‘Global Shear Vector’ Metric Provides New Insights Into Spinal Alignment

Tool correlates well with sagittal vertical axis and quality-of-life measures

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illustration of an alzheimer brain and a packet of sildenafil pills
March 11, 2024/Neurosciences/Research

Sildenafil as an Alzheimer’s Candidate Drug: Further Support From Insurance Database and Mechanistic Studies

Real-world claims data and tissue culture studies set the stage for randomized clinical testing

Brain mapping

Noninvasive Technology Enhances Ability to Map Brain Activity to Track Behavior Change

Preclinical work promises large-scale data with minimal bias to inform development of clinical tests

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December 11, 2023/Behavioral Health

American Psychiatrists Reveal Changing Attitudes About the Therapeutic Use of Classic Hallucinogens

Study shows a growing openness to the clinical potential of psychedelic treatments

Feixiong Cheng, MD

An All-Fronts Approach to Understanding and Overcoming Alzheimer’s Disease

A conversation with Feixiong Cheng, PhD, about his wide-ranging research initiatives

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October 27, 2023/Behavioral Health

75 Years Later: Cleveland Clinic Recalls Researchers’ Pivotal Role in Discovery of Serotonin

Finding changes the treatment landscape of psychiatric illness

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Advanced Computational and Imaging Tools Yield Insights Into Learning and Decision-Making

Research aims to extend observations of reversal learning in mice to human neurological disorders

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