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Research

hand of a person doing a crossword puzzle
March 13, 2025/Neurosciences/Research

Novel Tool Assesses Dynamic Neurocognitive Adaptation Across a Lifetime

Validated scale provides a method for understanding how lifestyle may protect against Alzheimer's

brain illustration with a focused inset section labeled "LCN"
February 25, 2025/Neurosciences/Research

Deep Brain Stimulation for Brain Injury Rehab: Do Benefits Continue After Neurostimulation Stops?

Promising preclinical research indicates functional motor recovery is durable

woman in red shirt standing beside a sign for clinical study recruitment
February 20, 2025/Neurosciences/Research

The Cleveland Clinic Brain Study at 3 Years: Initial Insights, Surprises and Next Steps

A principal investigator of the landmark longitudinal study shares interesting observations to date

Medical illustration of brain
January 6, 2025/Neurosciences/Research

Department of Defense Awards $3.4 Million to Advance a Tool for Assessing Return-to-Duty Readiness After Brain Injury

Cleveland Clinic researchers collaborate with Microsoft to create a product ready for the field

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Medical illustration of microglia
December 10, 2024/Genomic Medicine/Research

Network-Based Analyses Uncover How Harmful Microglia Form in Alzheimer’s Disease

Study identifies Ketorolac as a potential repurposable drug

Illustration of a brain
November 6, 2024/Neurosciences/Research

Genomic Analysis Finds Connections Between Transposable Elements and Alzheimer's Disease

Understanding TE involvement is a key to developing new treatments

Man on an exercise bicycle
October 29, 2024/Neurosciences/Research

New Parkinson’s Trial Focuses on Interplay Between Exercise and Genetics

Study aims to inform an enhanced approach to exercise as medicine

researcher in dark laboratory
September 12, 2024/Neurosciences/Research

Preclinical Imaging Research Aims to Help Refine Deep Brain Stimulation for Stroke Recovery

$3.2 million grant will fund use of calcium-based imaging to record neuronal activity in ischemia model

neurons, axons and synapses in the brain
September 5, 2024/Neurosciences/Research

A Case Study in Neurotherapeutic Clinical Trial Design and Conduct

New phase 1 trial showcases Neurological Institute’s interdisciplinary study capabilities

anatomic spine with vectors displayed

Novel ‘Global Shear Vector’ Metric Provides New Insights Into Spinal Alignment

Tool correlates well with sagittal vertical axis and quality-of-life measures

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