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Basic & Translational Science

CAR T-cell therapy

Metabolomic Screening Reveals Pre-Existing Signatures in Patients Treated with CAR T-Cell Therapy

Molecular markers could potentially predict major adverse side effects

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Platelet Activation Differs Between Men and Women in Myocardial Infarction and Beyond

Findings in both health and MI highlight need for sex-specific pharmacotherapy research

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Positive Early Results From Phase 3 Trials of COVID-19 Vaccine Candidates

High efficacy reported for vaccine candidates in interim analyses

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Exploring the Role of Immune Response in Parkinson Disease

Research consortium launches multisite investigations of the impact of aberrant immunity

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Potential Novel Therapeutic Strategy in Rhabdomyosarcoma Based on Ezrin-Radixin-Moesin Inhibition

Preclinical studies point to antitumor activity of the ERM inhibitor NSC668394

Melatonin may prevent COVID-19

Melatonin a Promising Candidate for Prevention and Treatment of COVID-19

After adjusting for comorbidities, melatonin usage was associated with reduced risk

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In Search of Predictive Biomarkers of Dementia in Parkinson Disease

$3.8M NIH grant fuels effort to develop a multimodal and multivariate model

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Dr. Jarek Maciejewski Receives Innovation Award for Genomic Discoveries in Hematologic Malignancies (Video)

Sones award honoree advancing knowledge in leukemia, bone marrow failure syndromes

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Studies of Sex-Related Molecular Differences in Glioblastoma Draw $10.4M in NIH Support

Funding expands work by consortium led by Cleveland Clinic Lerner Research Institute and CWRU

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Succession of Molecular Lesions Critical to Leukemia Disease Development

Mutational pattern in MDS is not random, study finds

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