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Basic & Translational Science

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Research on tPA Nanoconjugate Aims to Extend Thrombolysis Benefits to More Stroke Patients

$2M NIH grant will help see if dual-action agent lengthens treatment window

Lab research

Advancing Immunotherapy: A Conversation with Timothy Chan, MD, PhD

Meet the Director of Cleveland Clinic’s new Center for Immunotherapy and Precision Immuno-Oncology

Husni lab

Predicting Anti-TNF-Therapy Responsiveness

Defect in myosin binding may explain why a significant percentage of patients do not adequately respond to anti-TNF therapy

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Innovative Tools for Diabetes Management

Tools to aid in diagnosis, complication management and lifestyle interventions

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Network-Based Drug Discovery for the Emerging COVID-19 Epidemic

Minimizing the translational gap between preclinical testing and clinical outcomes

gut microbiota

Beta-Blockers’ Efficacy May Be Partly Explained By Newly Discovered Gut Microbial Metabolite

Phenylacetylglutamine acts via adrenergic receptors and is linked with cardiac events

deepDTnet, A network-based deep learning methodology,

Harnessing Artificial Intelligence for Drug Repurposing

deepDTnet receives provisional patent to accelerate drug repurposing and minimize the translational gap in development

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Common Measures of Immune Status, Inflammation Can Predict Mortality

A mortality risk profile based on lymphocyte count, red blood cell distribution width and C-reactive protein levels

Feixiong Cheng, MD

Network-Based Tool Predicts Disease Comorbidities

Identifying disease-disease relationships

Ultrasound image of the carotid artery

Machine Learning to Assess Stroke Risk

Noninvasive assessment of carotid artery plaque composition

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