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Basic & Translational Science

Genomic Laboratory Equipment

New Collaboration Moves the Needle on Precision Medicine

Cleveland Clinic and PGDx employ liquid biopsy technology to enhance patient care and research

Glioblastoma

Failed Alzheimer’s Drug Shows Promise for Treating Glioblastoma in Preclinical Study

BACE1 inhibitor reduces cancer progression in models of glioblastoma

Depiction of a blood clot forming inside a blood vessel. 3D illustration

Immune Checkpoint Inhibitors May Enhance Cancer-Associated Thrombosis

Common cancer therapy increases serious risks in murine models

Sildenafil

Sildenafil Emerges as a Candidate Drug for Alzheimer’s Disease

69% relative risk reduction in large database analysis prompts plans for mechanistic and phase 2 studies

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Dietary Nitrate Exerts Differing Platelet Effects in Men and Women

Provocative findings from a hypothesis-generating study

Ruth Keri, PhD

Study Uncovers Critical Roles of YES1 in Triple-Negative Breast Cancer Cells

Understudied Src Family Kinase may serve as a potential therapeutic target

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High-Fat Diet Linked to Aggressive Glioblastoma in Preclinical Study

Findings implicate hydrogen sulfide dysfunction, point to potential treatment strategies

CCC Tadiello 2507064 Breast cancer vaccine prep 10-25-21 LDJ

Cleveland Clinic Launches First-of-its-Kind Preventive Breast Cancer Vaccine Study

Retired-protein strategy represents new approach to immunization

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