Tag: alzheimer disease (AD)

pathology image of a Lewy body inclusion
February 15, 2024/Brain Health

Lewy Body Pathology Linked to Cerebral Amyloid Angiopathy in Alzheimer’s Disease Patients

Recognizing this association aids risk assessment before starting novel immunotherapies


Microglial Immunometabolism Endophenotypes Implicated in Sex Differences in Alzheimer’s Disease

Study suggests sex-specific pathways show potential for sex-specific therapeutic approaches


Does Sleep Dysfunction Help Explain Sex Differences in Alzheimer’s Incidence and Progression?

Novel research is comparing sleep measures to biomarkers of neurodegeneration

April 13, 2023/Brain Health

Markers of Metabolic Syndrome Linked to Cognitive Decline in MCI and Alzheimer’s

High plasma ApoA1 and TG/HDL-C ratio predict faster progression


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22-NEU-3482371 Alzheimers-brain-650×450
January 12, 2023/Brain Health

Does Peripheral Inflammation Drive Alzheimer’s Disease Progression?

New research explores the role of immune cell and blood-brain barrier changes


Deep Learning Framework Unveiled for Identifying Risk Genes and Drug Targets in Alzheimer’s Disease

Open-source artificial intelligence technology uses human genetic data to find candidate drugs

December 13, 2022/Geriatrics

What’s the State of Anti-Amyloid Therapy in the Wake of Initial Clarity AD Findings?

Experts weigh in on the amyloid hypothesis and how to use lecanemab if approved


Big Patient Data Analyses Pinpoint Telmisartan as a Candidate Drug for Alzheimer’s in Black Adults

Findings underscore need for racial diversity in ongoing and future trials

October 31, 2022/Brain Health

Alzheimer’s Disease in Women: How Our Understanding Continues to Evolve

Investigative highlights include hormone therapies, biomarkers and early lifestyle interventions


Sildenafil Emerges as a Candidate Drug for Alzheimer’s Disease

69% relative risk reduction in large database analysis prompts plans for mechanistic and phase 2 studies

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