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Tag: alzheimer’s disease

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Rapidly Progressive Alzheimer’s Disease Has Distinct CSF Protein Signatures

Proteins related to altered immune response are potential biomarkers of the rare AD variant

illustration of an alzheimer brain and a packet of sildenafil pills
March 11, 2024/Neurosciences/Research

Sildenafil as an Alzheimer’s Candidate Drug: Further Support From Insurance Database and Mechanistic Studies

Real-world claims data and tissue culture studies set the stage for randomized clinical testing

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November 27, 2023/Neurosciences/Brain Health

Prospective Study Hints at Age-Related Memory Advantages for Rural Dwellers

For some older adults, a rural setting in late life may be protective

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February 17, 2023/Neurosciences/Brain Health

Dementia With Initial Nonamnestic Symptoms Predicts Rapid Course

New findings have important implications for clinical trial design

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Leverenz, MD
November 8, 2022/Neurosciences/Podcast

What Postmortem Brain Autopsy Can Reveal About Alzheimer’s Disease (Podcast)

Studying brain samples can advance understanding of mechanisms and impact clinical care

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The Role of Circadian Rhythm and Sleep Dysfunction in Alzheimer’s Pathophysiology

New insights into shared inflammatory pathways and immune responses

Schizophrenia concept
April 16, 2021/Geriatrics

Making the Differential Diagnosis in Dementia (Podcast)

Alzheimer’s, Lewy body and other etiologies have distinct presentations and treatments

genetics and alzheimer's disease
April 12, 2021/Genomic Medicine

Tumor Necrosis Factor Pathway Contributes to Resilience in Alzheimer’s Disease

TNFRSF1B gene variant associated with slower progression, offering potential drug target

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February 22, 2021/Geriatrics

In Search of Disease-Modifying Treatment for Alzheimer’s (Podcast)

An update on biomarkers and various therapies in development

Dr. Pillai with patient
February 17, 2021/Geriatrics

APOE e4 Allele Presents With Varying Faces in Different Neurodegenerative Diseases

Cohort study characterizes symptomatology by Alzheimer’s and Lewy body pathology

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