The factor Xa inhibitor failed to demonstrate noninferiority to warfarin in preventing valve thrombosis or thromboembolism in conjunction with the bileaflet On-X mechanical valve.
In-hospital mortality following LAAC was no higher in patients aged 80 or older than in their younger counterparts, a large database analysis shows. We share insights on LAAC in this population from the Cleveland Clinic experience.
Despite lack of labeling or much safety data, use of DOACs following surgical heart valve replacement is not insignificant — and is growing. So finds a new national cohort study.
Continuous quality improvement efforts and support for caregivers lead to national recognition for extracorporeal membrane oxygenation (ECMO) at Cleveland Clinic Children’s.
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Severe COVID-19 is associated with a hypercoagulable state that often requires changes to usual inpatient anticoagulation strategies. We share our approach, including thromboprophylaxis protocols and a case vignette.
If this new prospective multicenter study meets its endpoints, aortic valve replacement with a mechanical valve will likely become more attractive to younger patients.
A new PARTNER 2 analysis suggests a lack of short-term impact of early anticoagulation on hemodynamics and most clinical outcomes regardless of whether replacement was percutaneous or surgical. But definitive guidance awaits randomized investigation.
The newly approved WATCHMAN™ device can prevent stroke in high-risk patients with nonvalvular atrial fibrillation. But when exactly is left atrial appendage closure preferable to warfarin therapy?
Two recent sizeable retrospective reviews yield insights from Cleveland Clinic’s more than three decades of experience repairing bicuspid valves and using bioprostheses for aortic valve replacement.