Patients with uveal melanoma metastatic to the liver who present without symptoms and receive local therapy as first-line treatment have better survival outcomes those who present with symptoms and receive other first-line therapies, a Cleveland Clinic study has found.
An animal model of brachytherapy-induced retinopathy would help investigators understand the underlying pathophysiological mechanisms. Cleveland Clinic researchers are creating one, which could eventually help test promising therapeutics.
A 54-year-old man on immunosuppressant therapy after a renal transplant two years before presented at Cole Eye Institute with a recurrent ocular surface tumor. After five years, the patient’s final visual acuity is 20/20 without evidence of local recurrence, radiation retinopathy or optic neuropathy. To our knowledge, this is the first reported case of primary ocular or conjunctival myofibrosarcoma.
Patients with choroidal metastases can see flashing lights, floating spots and have distortion of their vision. A careful history and physical examination can uncover signs and symptoms of hidden cancer.
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New Cleveland Clinic research shows that serial hepatic USG — paired with confirmatory CT/MRI scans when needed — has high sensitivity and specificity for detecting asymptomatic uveal melanoma metastases.
Director of Cleveland Clinic’s Department of Ophthalmic Oncology discusses most effective treatments for both localized and multifocal ocular adnexal lymphoma, a rare form of lymphoma.
As optical coherence tomography quickly evolves to more specific modalities with higher resolution and enhanced depth, its importance in clinical practice will grow, particularly with more portable units.