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Tag: castration-resistant prostate cancer (CRPC)

February 3, 2023/Basic & Translational Science

National Prostate Cancer Trial Testing Therapy Based on Cleveland Clinic Molecular Discovery

Clinical trial strategy was developed through research on a gene associated with treatment-resistant prostate cancer

April 1, 2020/Cancer

New Genetic Test May Mean Better Outcomes in Advanced Prostate Cancer

Cleveland Clinic-developed test identifies variant of HSD3B1 gene

May 4, 2019/Basic & Translational Science

A New Paradigm for Advanced Prostate Cancer Clinical Trials

What's driving tumor progression is the key, says Nima Sharifi, MD

July 2, 2018/Basic & Translational Science

Prostate Cancer Drug Metabolite May Fuel Cancer Cells

Men with the HSD3B1(1245C) variant metabolize abiraterone differently

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June 26, 2014/Urology & Nephrology/Urology

Researchers Find Mutation That Promotes Hormone Therapy Resistance

Alteration ‘opens the floodgates’ to DHT synthesis in prostate tumors

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