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Novel insights from a postmortem study combining imaging, pathology and clinical perspectives
MRI classifier identifies a subset of patients with disease marked by cortical atrophy, not demyelination
A focus on biological processes should improve both research and management
Model of viral encephalomyelitis shows links with CNS recovery from inflammation and damage
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Shortcomings in specificity show influence of cortical changes beyond demyelination
Finding suggests need for multifront therapeutic approach
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