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Multiple Sclerosis

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Vidofludimus for Progressive MS: No Impact on Brain Atrophy but Hints of a Role for Disability

Mixed results from phase 2 CALLIPER trial of novel dual-action compound

illustration of myelin sheaths wrapped around neuron axons

Revised McDonald Criteria for Multiple Sclerosis: A Big Step Toward Biomarker-Driven Diagnosis

A co-author of the new recommendations shares the updates you need to know

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De-Escalation of Disease-Modifying Therapies in MS: A Real-World Look at Outcomes

Rebound risk is shaped by patient characteristics and mechanism of action of current DMT

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Tool Shows Promise for Individualized Decision Support on Stopping Disease-Modifying Therapy for Multiple Sclerosis

First-of-kind prediction model demonstrates high consistency across internal and external validation

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Ocrelizumab Associated With Nearly Twofold Increase in Serious Infections Vs. Platform Injectables in Multiple Sclerosis

Real-world study also finds no significant rise in ocrelizumab-related risk with advanced age

two brain MRIs side by side with red circles on them

Cognitive Impairment in Multiple Sclerosis Linked to Rapid Thalamic Atrophy

Machine learning study associates discrete neuropsychological testing profiles with neurodegeneration

two brain MRIs side by side

Brain Volume Changes and Disability in MOGAD: Defining Differences From Other Demyelinating Diseases

Despite less overall volume loss than in MS and NMOSD, volumetric changes correlate with functional decline

two brain MRIs with red arrows indicating spots of interest

Paramagnetic Rim Lesions Are Highly Accurate for MS Diagnosis at First Presentation

This MRI marker of inflammation can help differentiate MS from mimics early in the disease

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Accelerated Aging May Be Present in the Youngest Patients With Multiple Sclerosis

Case-control study yields evidence of epigenetic aging in pediatric-onset MS

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