Intravenous golimumab is both safe and effective over a one-year treatment period for patients with psoriatic arthritis. Rheumatologist Elaine Husnie, MD, MPH, discusses the findings.
PROMIS Measures Are Associated with Disease Activity in Psoriatic Arthritis
Clinical disease activity measures provide only a limited assessment of health domains that are important to patients, which may lead to under- or over-treatment and patient dissatisfaction. Rheumatologist Elaine Husni, MD, MPH, explains the findings of her recent study, and why it’s so important for clinicians to listen carefully when patients report symptoms.
Targeting Tumor Necrosis Factor Pathways in Psoriatic Diseases: The Next Step
Preclinical models suggest that specific blockade of TNFR2 may significantly reduce inflammation and ameliorate signs of psoriatic diseases, while maintaining normal immune response in the host, including the ability to combat infection and cancer. In this article, M. Elaine Husni, MD, MPH, highlights her latest research and discusses her plans to use her new R01 grant to continue her translational work.
Targeting Biomarkers of Nitric Oxide and Endothelial Dysfunction in RA and PsA
Translational work combining human plasma studies and previous mouse model data will enable identification of new, precise biomarkers and potential treatment pathways that may help pinpoint and treat RA and PsA patients at increased risk of CV disease.
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Relieving Knee Osteoarthritis Pain: Is There a Better Way?
Does the addition of intra-articular HA injections to PT have a synergistic effect in alleviating pain and reducing disability in patients with knee OA?
Bariatric Surgery: A Fix for OA?
Our findings reveal that bariatric surgery and the resulting massive weight loss have the potential to considerably improve health-related quality of life for patients suffering from OA for up to three years.
PRECISION Results = Precisely Tailored Arthritis Treatment
Subgroup analyses from the PRECISION trial allow rheumatologists to offer individualized treatment to OA and RA patients on chronic NSAIDs.
Advances in the Treatment of Knee Osteoarthritis
Orthopaedic surgeons at Cleveland Clinic will perform the first prospective, double-blind, randomized, placebo-controlled, multicenter feasibility study to examine the safety and efficacy of pulsed electromagnetic fields knee braces in the treatment of knee osteoarthritis.
Tapering DMARDs: Where are we now?
The promise of drug-free RA remission is appealing, but many questions remain. Explore answers at Biologics Summit VII in April 2017.
Asymmetric Dimethylarginine as a Novel Biomarker for Cardiovascular Risk in Psoriatic Diseases
Our laboratory tests whether aberrant levels of plasma and tissue L-arginine metabolites serve as an early, non-invasive predictor of CV disease in psoriatic patients.