Some patients with familial adenomatous polyposis treated with a combination of sulindac and eflornithine have a decreased risk of progression and a delayed need for lower gastrointestinal surgery.
Results of a new phase 3 study show promising results for a two-drug combination in reducing the need for surgery in patients with familial adenomatous polyposis (FAP).
Laparoscopic reoperative ileal J pouch anal anastomosis (IPAA) is feasible, safe and has better outcomes than laparotomy.
Cleveland Clinic research highlights the inconsistency of Spigelman classification as a risk predictor for duodenal cancer in familial adenomatous polyposis patients, suggesting that the formula for staging duodenal polyposis may need to be adjusted.
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A surprising rise in gastric cancer among FAP patients caused physicians to change their surveillance techniques.
About 20 percent of FAP patients suffer from PTSD symptoms. James Church, MD, and his colleague performed groundbreaking research that demonstrates the need for specific trauma therapy.
As a GI, how do you make sound judgments to balance cancer prevention and quality of life in patients with inherited colorectal cancer predisposition syndromes? Here Dr. James Church explains Cleveland Clinic’s approach.
Patients with inherited cancer syndromes benefit from a Cleveland Clinic multidisciplinary referral network that provides a formal thyroid cancer screening process.