Little is known about the genes that may influence Parkinson’s disease risk in Latinos, but a multinational research consortium is working to change that. Hear from the consortium’s U.S. coordinator in our latest podcast episode.
We explain why we’ve launched an Epilepsy Precision Medicine Fellowship and how it’s designed to empower tomorrow’s epileptologists to apply neurogenetics to improve patient care
The first genome-wide association study of Parkinson’s disease in Latinos has identified several potential risk loci of interest in this understudied population.
Initial results from one of the largest studies in children and adolescents to investigate the role of COMT polymorphism suggest the promise of early identification of individuals who may be more vulnerable to self-harm and suicidality.
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New funding will expand the LARGE-PD cohort study of Parkinson disease in Latinos to include a genome-wide association study and develop a Latino-specific polygenic risk score for PD.
A study combining genetic data and statistical modeling has generated some of the first epidemiologic estimates for neurodevelopment disorders caused by de novo variants. It promises much-needed guidance on priorities around these rare diseases.
Researchers have developed the first polygenic risk score that distinguishes on a cohort level between patients with epilepsy and controls, as well as between patients with generalized and focal epilepsies.
Should everyone with dilated cardiomyopathy undergo a genetic profile? This discussion with a heart failure and genetics expert offers guidance until results of the DCM Precision Medicine Study come in.
No large-scale Parkinson’s disease genetic studies have ever been conducted in Latino populations — until now. The leader of the LARGE-PD cohort study explains its rationale and goals.
The grant will fund exploration of whether the genetic composition of lung cancer cells can predict response to and perhaps guide strategy for radiotherapy.