Lower doses of gonadotrophin in minimal stimulation in vitro fertilization increases oocyte quality in select patients. Fertility specialist Laura Detti, MD, explains how her team aims to increase affordability and access to the fertility treatment.
In vitro fertilization (IVF) has been vastly improved over the past few years with a transition to blastocyst state cryopreservation and transfer. Fertility experts Nina Desai, MD, and Elliot Richards, MD, share insights from the largest, prospective, randomized study to date of embryo development and live birth rates between sibling embryos cultured in two different single-step media.
For the second time in its clinical trial, a Cleveland Clinic patient has given birth after receiving a transplanted uterus from a deceased donor. In this article, Ob/Gyns on the transplant team provide a closer look at the transplant procedure and fertility treatments provided to a patient with MRKH syndrome.
Time-lapse technology allows the continuous monitoring of embryonic development, aiding in embryonic selection. Microbiologist Nina Desai, PhD, explains the development of a predictive model for euploid blastocyst selection.
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Sperm DNA fragmentation has been suggested to be a contributor to male infertility and lower pregnancy outcomes. However, the degree to which DNA fragmentation influences outcomes in IVF is still controversial. Integration of time-lapse microscopy (TLM) into IVF labs allows more in-depth analysis of embryo developmental kinetics than was previously possible with conventional microscopy.
New technology is revealing which sperm are the most robust, increasing the success rate that azoospermic men can father a child through in vitro fertilization.
Using time-lapse images, Cleveland Clinic scientists looked at how embryo cell division rhythms and characteristics might affect embryo chromosomal integrity, finding delayed blastulation led to greater aneuploidy.