Emerging sex differences in multiple aspects of this lethal brain cancer likely help explain the disease’s more favorable incidence and prognosis in females. And they may point to new targeted therapies.
Microglia can be both protective and damaging to the brain. A neuroscientist explains how his lab is working to characterize responses and pathways that alter key microglial interactions in health versus disease.
Recent findings in the mouse suggest that microglia’s protective role might be harnessed to improve prognoses across many neurologic diseases. The researchers explain their work and look ahead to next steps.
Microglia have been identified as bad actors in the development of chronic brain disease. But these debris-collecting cells actually perform good deeds after traumatic injury.