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Radiation to the pelvis from cancer treatment made the traditional treatment path unavailable
Poor response may be due to different tumor biology
Study sheds light on distant metastasis rates between upfront surgery and Watch & Wait strategies
Findings could help promote organ preservation
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The retrospective study also identified predictors for which patients would likely achieve a complete response from TNT
Fewer patients eligible for sphincter-preserving surgery during pandemic
Tumor downsizing and en bloc resection are keys to treatment
Study compares open versus laparoscopic abdominoperineal resection outcomes
Stoma-avoidance, quality of life drive evolving care
Avoiding abdominoperineal resection
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