Cutaneous Adverse Effects of Small-Molecule Tyrosine Kinase Inhibitors

Biologic therapies, such as tyrosine kinase inhibitors (TKIs), have revolutionized medicine and offer targeted therapy for an increasing number of diseases; however, along with these advances and their ensuing expanded use have come many unique adverse effects. In this article, dermatologists review how to manage cutaneous adverse effects of TKIs and when to consult a dermatologist.