What is the role of molecular profiling in risk stratification?
Majority of patients achieve complete pathologic response after four-dose cemiplimab therapy
Impressive progression-free survival observed in phase 2 study
Pilot Study at Cleveland Clinic is Testing Feasibility and Biodistribution
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Findings support need for personalized disease management
Pathogenic POLE/POLD1 mutations lead to improved response to immune checkpoint blockade therapy
Tumor genomics offer clues for identifying high risk of relapse
Blinatumomab followed by POMP maintenance shows effectiveness for newly diagnosed patients
Study to test efficacy of immunotherapy with chemotherapy and radiation
Molecular targets may offer noncytotoxic treatment path
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