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Mounting support for the newly described microstructure from a 7T MRI and electroclinicopathologic study
Confirming the diagnosis is only the start of the journey
Communication is particularly critical in this often-misdiagnosed disorder
New Cleveland Clinic fellowship fosters expertise in the genetics of epilepsy
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The neuroactive steroid significantly reduces seizures related to CDKL5 deficiency disorder
Integrates genetic and clinical data to distinguish from GEFS+ and milder epilepsies
Randomized trial will follow 1,000 patients to explore potential adjunctive role
Consider 36-hour standard, with certain risk factors prompting longer or shorter windows
Machine learning models shown to accurately separate lesions from normal brain, distinguish lesion subtypes
But such EEG findings should not preclude tapering of antiseizure medications
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