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51% of patients with resectable cutaneous squamous-cell carcinoma achieved a pathological complete response and 13% achieved a pathological major response to the anti–programmed cell death 1 (PD-1) monoclonal antibody cemiplimab, according to …
A new phase 3 study has begun enrolling patients with high-risk, locally advanced cutaneous squamous cell carcinoma (cSCC) to evaluate the curative potential of adjuvant pembrolizumab. Cleveland Clinic oncologist Jessica Geiger, MD, introduced the …
The process of staging cutaneous squamous cell carcinoma (CSCC) is typically done using the American Joint Commission on Cancer (AJCC) and Brigham and Women’s Hospital (BWH) tumor classification systems and is based on tumor …
… cohorts.Clinical significanceBased on their findings, the research team argues that S-ITM should be codified in cutaneous squamous cell carcinoma staging systems, similar to what has been done in Merkel cell carcinoma and melanoma …
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… with the most effective course of treatment.Rethinking resectionSurgical resection is the standard of care for advanced cutaneous squamous cell carcinoma, but it would have been a major undertaking in this case. “By this point …
… and American Joint Committee on Cancer (AJCC) staging systems do a good job of predicting outcomes for cutaneous squamous cell carcinoma. However, we believe that we can improve on prognosticating to determine which tumors need …
Immunosuppressed patients with lower-risk cutaneous squamous cell carcinoma (cSCC) who score higher on the 40-gene expression profile (40-GEP) biomarker test are at greater risk of recurrence, according to a study presented by …
Adjuvant pembrolizumab did not significantly improve progression-free survival compared with placebo in patients with high-risk, locally advanced, cutaneous squamous cell carcinoma (cSCC) following surgery and radiation, according to a Cleveland Clinic-led randomized …
… Genitourinary Cancers, with presentations on topics such as individualized stereotactic ablative radiotherapy (ISABR) and SABR for renal cell carcinoma, trimodality therapy for bladder cancer and re-irradiation for local recurrence of prostate cancer.“High-dose …
By Atul Mehta, MDAs use of lung transplant (LT) becomes more common, pulmonologists should be aware of post-transplant dermatologic complications. In a recent pictorial review in CHEST, my colleagues and I describe the pathogenesis …
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