Cleveland Clinic’s Genomic Medicine Institute is looking at the use of sophisticated 3-D modeling to help discern nuanced but important structural differences between germline PTEN variants associated with and predictive of a patient’s clinical condition.
Cleveland Clinic’s Charis Eng, MD, PhD, received the American Cancer Society’s 2018 Medal of Honor for clinical research. Dr. Eng is acclaimed for linking certain genetic mutations to cancer risk.
A new study provides initial evidence that differences in gut microbiota composition may indicate whether or not a PHTS patient will develop cancer.
A study comparing healthy and malignant breast tissue found more Methylobacterium in malignant breast tissue.
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A case of developmental delay, hypotonia and macrocephaly in a toddler leads to discovery of identical PTEN gene mutations in multiple family members, thanks to a multidisciplinary PTEN clinic.
This study of a family with Cowden Syndrome and thyroid cancer revealed the role of USF3 and potential therapeutic breakthroughs.
Investigators are analyzing microbiomes in several solid tumors. If microbiome elements are involved in carcinogenesis, they could serve as biomarkers for progression and prognosis, as well as therapeutic targets.
Patients with inherited cancer syndromes benefit from a Cleveland Clinic multidisciplinary referral network that provides a formal thyroid cancer screening process.
Charis Eng, MD, PhD, Chair and Director of Cleveland Clinic’s Genomic Medicine Institute, shares her views on genetics-related Top 10 Innovations.
Recording patients’ family medical history and including it in their medical record is important in prevention, risk reduction and early detection of disease.