A new study confirms that cortical-sparing surgery can be a safe option for patients with genetic disease, who are at greater risk for developing subsequent tumors. In this article, Charis Eng, MD, PhD, explains the research and its implications for clinical management.
A new $1.6 million Gray Foundation grant will enable cancer genetics expert Charis Eng, MD, PhD, and colleagues to advance their promising preliminary research into the breast microbiome’s role in cancer risk, development and progression.
Cleveland Clinic’s Genomic Medicine Institute is looking at the use of sophisticated 3-D modeling to help discern nuanced but important structural differences between germline PTEN variants associated with and predictive of a patient’s clinical condition.
Cleveland Clinic’s Charis Eng, MD, PhD, received the American Cancer Society’s 2018 Medal of Honor for clinical research. Dr. Eng is acclaimed for linking certain genetic mutations to cancer risk.
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A new study provides initial evidence that differences in gut microbiota composition may indicate whether or not a PHTS patient will develop cancer.
A study comparing healthy and malignant breast tissue found more Methylobacterium in malignant breast tissue.
A case of developmental delay, hypotonia and macrocephaly in a toddler leads to discovery of identical PTEN gene mutations in multiple family members, thanks to a multidisciplinary PTEN clinic.
This study of a family with Cowden Syndrome and thyroid cancer revealed the role of USF3 and potential therapeutic breakthroughs.
Investigators are analyzing microbiomes in several solid tumors. If microbiome elements are involved in carcinogenesis, they could serve as biomarkers for progression and prognosis, as well as therapeutic targets.
Patients with inherited cancer syndromes benefit from a Cleveland Clinic multidisciplinary referral network that provides a formal thyroid cancer screening process.