Balloon Kyphoplasty for Intractable Pain in Pediatric Vertebral Fracture
In this series with three seriously ill patients, a vertebral stabilization technique dramatically decreased pain and increased function in the immediate postoperative period.
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Osteopenia and osteoporosis are common side effects of both steroid use and chemotherapy in children and adults. Both conditions can potentially lead to vertebral compression fractures. Vertebral compression fractures can be a significant source of debilitating pain, psychosocial decline and physical impairment in patients of all ages.
Vertebroplasty and balloon kyphoplasty are percutaneous vertebral augmentation techniques that have been used extensively with good to excellent results in adults to control pain following vertebral compression fractures. To date, their use in children has been limited, and few studies and no formal indications exist.
We retrospectively reviewed outcomes for three pediatric patients who underwent balloon kyphoplasty at our institution to address their intractable pain from vertebral compression fractures between 2007 and 2013. Our results were published in the Journal of Pediatric Othopaedics.
The underlying diagnoses for these patients (average age 12.3 years, all male) were:
Preoperative pain scores were very severe (8 to 9 on a 10-point scale), impacting the children’s ability to independently ambulate. One patient even required elective intubation due to respiratory distress secondary to pain. Two of the three patients underwent multilevel procedures.
At an average of 3.6 weeks postsurgery, patient pain was improved to an average of 2/10. Two of the three patients were able to sit, stand and walk independently at follow-up. The third patient (with IPEX-like syndrome) was successfully extubated one-week postoperatively. He was capable of normal activity, including playing basketball, at follow-up about two years after balloon kyphoplasty treatment. No complications were encountered in this small case series.
Our follow-up was short in two of the three patients because of their early demise due to underlying oncological disease.
In our series, balloon kyphoplasty dramatically decreased pain and increased function in the immediate postoperative period in each of the patients treated. This small study provides initial information on the usefulness and safety of this procedure in this subset of seriously ill patients. Further research is necessary to establish indications for balloon kyphoplasty in pediatric patients.
Dr. Goodwin is Director, Center for Pediatric and Adolescent Orthopaedics; Dr. Gurd is Head of Pediatric Spinal Deformity Surgery; Dr. Kuivila is staff physician, Pediatric Orthopaedic Surgery, Vice Chair for Education, Orthopaedic & Rheumatologic Institute, and Residency Program Director, Orthopaedic Surgery; Dr. Hanna is Director, Pediatric Bone Marrow Transplantation, Department of Pediatric Hematology and Oncology, Cleveland Clinic Children’s Hospital.