Endocrinopathies occur in about 10% of patients who receive immune checkpoint inhibitors. Cleveland Clinic researchers review the them and look at principles of management.
ASCO Releases New Guidelines for Immunotherapy and Biomarker Testing in Recurrent and Metastatic Head and Neck Cancers
New guidelines support oncologists in treating recurrent and metastatic head and neck cancers
Case Report: Immunotherapy + Vaccine Helps 62-Year-Old with Colorectal Cancer
A patient opts for a novel clinical trial and thrives with stage 4 colorectal cancer.
FDA Approves New Treatment Regime for Advanced Liver Cancer
In May, the FDA approved atezolizumab in combination with bevacizumab for newly diagnosed patients with hepatocellular carcinoma.
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Polymyalgia Rheumatica-Like Syndrome from Checkpoint Inhibitor Therapy
Is checkpoint inhibitor-related polymyalgia rheumatica (PMR) distinct from the classic rheumatic disease, or does it represent new clinical variants with potentially different pathogenesis, clinical course and treatment responsiveness? Rheumatologist/immunologist Cassandra Calabrese, DO, discusses her research, which identified clinical features that are unusual in idiopathic PMR.
Rheumatic Immune-Related Adverse Events from Checkpoint Inhibitor Therapy: Update
A common occurrence in the age of cancer immunotherapy, immune-related adverse events require multidisciplinary collaboration for investigation and optimal management. Drs. Cassandra and Leonard Calabrese discuss the ever-evolving field and the need for continuing education.
A Novel Tumor Board for Patients with Immune-Related Adverse Events
The goal of the tumor board is to discuss new and/or challenging cases of irAEs, review the extant literature and receive input on interprofessional management.
Checkpoint Inhibitor Therapy for Patients with Immune-Mediated Inflammatory Diseases (Video)
Checkpoint inhibitor therapy for cancer holds great potential for durable response rates, but immune-related adverse events may be its Achilles’ heel.