Locations:
Search IconSearch

The Leg Bone’s Connected to the Arm Bone: Surgeons Use Fibula to Reconstruct Humerus in Unique Pediatric Sarcoma Case

Orthopaedic oncologist discusses the complex case

21-ORT-2083511-Humerus-Osteoasarcoma-Using-Fibula

Nathan Mesko, MD, an orthopaedic oncologist at Cleveland Clinic, says his job often requires creative solutions to restore function.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

This was certainly true in a recent case when a 5-year-old patient presented to Cleveland Clinic with substantial swelling in his right shoulder, his dominant arm. A thorough workup revealed that the patient had humeral osteosarcoma. The pediatric oncology team began chemotherapy immediately, and the tumor responded nicely over several months. Next, was Dr. Mesko’s challenge.

“The challenge of reconstruction was to provide this energetic, fun-loving 5-year-old with an arm that allowed his humerus and elbow to serve as a working platform for his hand while saving all of the important nerves and blood vessels in his arm, giving him a chance at some form of growth in that arm,” he explains.

Utilizing the free fibula transplant technique

Dr. Mesko shares more details about this case, including a collaboration with Graham Schwarz, MD, of Cleveland Clinic’s Department of Plastic Surgery. The teams worked together, utilizing a free fibula transplant technique to reconstruct the patient’s humerus. “At three months, the patient was feeling like himself again, and the real challenge was trying to keep a 5-year-old down.” Learn how this particular challenge was failed, and more about this unique case in the video below:

Extraordinary Humerus Osteosarcoma Case Using a Fibula

“One of the most fun parts about being an orthopaedic oncologist is utilizing creativity to create function. Bone and soft tissue tumors oftentimes pick difficult locations when it comes to resection and reconstruction, and in children in particular this can be a challenging puzzle. Children present with these puzzles, forcing the surgical and oncological teams to take into account growth of the extremity, small size of the anatomy and the parental anxiety that can surround the cancer treatment of their precious loved one,” says Dr. Mesko.

Advertisement

Related Articles

Older man exercising by walking outside

Total Hip Arthroplasty Outcomes Remain Exceptionally Strong in 8-Year PROMs Analysis

Study highlights the need for objective functional measures as value-based care expands

Man with hand on lower back indicating back pain

Back or Contralateral Hip Pain May Limit Meaningful Improvement After THA

Reduces likelihood of achieving CMS-defined substantial clinical benefit at one year

Older adults walking outside while checking step count on wrist device

Wearable-Device Data Challenge Assumptions About Recovery After Total Knee Arthroplasty

Step counts suggest recovery is more variable and individualized than commonly believed

Patient using force plate

Advancing Athlete Recovery: The Role of Biodex Isokinetic Testing and Force Plates

Innovations and practical insights for safe return to sport after lower-limb injury

Woman with a physical therapist moving her knee
April 29, 2026/Orthopaedics/Hip & Knee

How Prehabilitation Prepares Patients for Total Joint Replacement

Physical therapy before surgery is intended to optimize outcomes after surgery

Man walking with hip pain

Arthroplasty Should Be Considered ‘Essential Surgery’ Due to Global Disease Burden

Recognition could help guide health policy, workforce development and resource allocation worldwide

Illustration of osteosarcoma shoulder procedure
April 8, 2026/Orthopaedics/Tumor

Innovations That Are Transforming Osteosarcoma Outcomes

The rare and aggressive form of bone cancer requires specialized treatment, but new and emerging therapies are providing hope for patients

clinician showing model of knee to patient

Return to Sport Rates Following Total Knee Arthroplasty

With a better understanding of timelines and contributing factors, clinicians can help athletes undergoing TKAs set realistic expectations

Ad