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Preventive Cardiology

Lp(a) particles floating among red blood cells

Lepodisiran’s Large, Durable Lp(a) Reductions in Phase 2 Trial Boost Anticipation of Phase 3 Results

Small interfering RNA lowered lipoprotein(a) by 94% during six-month follow-up after a single dose

blood pressure cuff on a woman's arm

Lorundrostat Shows Continued Promise Against Uncontrolled Hypertension

Phase 2b trial of aldosterone synthase inhibitor also finds no benefit from dose escalation

edge of an apolipoprotein particle

Small-Interfering RNA Shows Cumulative Lp(a) Reduction With Successive Doses

Phase 2 trial of zerlasiran yields first demonstration of longer effect with each dose of an siRNA

gut microbes in the human intestine

Gut Microbial TMAO Pathway Associated With Incident Heart Failure

Metabolites from animal product substrates implicated in heart failure development in community cohorts

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angiogram showing microvascular disease

Bringing More Options to Bear in CAD – Part 2: Meeting Needs of Special Patient Populations

Resourceful approaches to the care of patients with microvascular disease and elevated Lp(a)

chemical structure of erythritol drawn in a teaspoon

Evidence Mounts That Sugar Substitute Erythritol Raises Cardiovascular Risk

Study authors urge reevaluation of the sweetener’s safety designation by food regulators

nutrition label of product containing xylitol

Another Sugar Substitute, Xylitol, Is Linked to Heightened Cardiovascular Risk

Studies reveal increased cardiac events, enhanced platelet reactivity and thrombotic potential

LDL cholesterol particle with male and female symbols atop it

CLEAR Outcomes Subanalysis Shows Bempedoic Acid’s Clinical Benefits Apply Equally to Women and Men

Reassurance from the lipid outcomes trial with the highest percentage female enrollment to date

older woman using computer

Web App Enables Safe, Effective Nonprescription Statin Use

Tech-assisted self-selection concurred with clinician-assessed eligibility in >90% of cases

photo of grains and niacin supplement pills

Link Discovered Between Excess Niacin and Cardiovascular Disease

Newly identified pathway may explain the so-called niacin paradox

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