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Heart, Vascular and Thoracic

Lipoproteins

Novel siRNA Reduces Lipoprotein(a) by More Than 90% for 48 Weeks

Undetectable levels achieved for nearly nine months in phase 1 trial

illustration of tricuspid valve regurgitation

TRILUMINATE Health Status Analysis: T-TEER Patients Likelier to Be ‘Alive and Well’ at 1 Year

Investigators conclude that improved self-reports go beyond possible placebo effect for severe TR

HVI_Kelley_4277155_Patient Procedure Shoot- First in Human Trial
October 27, 2023/Genomic Medicine

Cleveland Clinic Treats First Patient With Investigational Gene Therapy for Hypertrophic Cardiomyopathy

One-time infusion of adenovirus-based therapy is designed to restore heart muscle function

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3D rendering of upper esophageal reflux in a male

Novel Tool Holistically Assesses Patient-Reported Outcomes of Esophageal Conditions

Going beyond the Eckardt symptom score to evaluate dyspepsia, eating and symptom “bother”

maps for ventricular tachycardia ablation

Monomorphic VT Electrical Storm: Is Ischemic or Coronary Evaluation Needed?

Study finds that in the absence of ACS, the yield is low and outcomes are unaffected

illustration of coronary artery with calcified plaque

Coronary Artery Calcium Scoring Improves Accuracy of Cardiovascular Risk Screening

Observational study supports adding CAC score to traditional risk factors for precision medicine approach

Blood pressure check

Lorundrostat Safely Lowers Blood Pressure in Uncontrolled Hypertension in Phase 2 Trial

Results inform dose selection for further trials of the aldosterone synthase inhibitor

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