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Tag: dyslipidemia

LDL cholesterol particle with a DNA double helix on top of it

CRISPR-Cas9 Gene Editing for Refractory Dyslipidemia Shows Safety and Preliminary Efficacy

First-in-human phase 1 trial induced loss of function in gene that codes for ANGPTL3

Lp(a) particles floating among red blood cells

Lepodisiran’s Large, Durable Lp(a) Reductions in Phase 2 Trial Boost Anticipation of Phase 3 Results

Small interfering RNA lowered lipoprotein(a) by 94% during six-month follow-up after a single dose

older woman using computer

Web App Enables Safe, Effective Nonprescription Statin Use

Tech-assisted self-selection concurred with clinician-assessed eligibility in >90% of cases

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photo of grains and niacin supplement pills

Link Discovered Between Excess Niacin and Cardiovascular Disease

Newly identified pathway may explain the so-called niacin paradox

19-HVI-1792159; Steven Nissen, M.D., M.A.C.C.; Mike Viars

Lipoprotein(a): Progress on One of the Last Untreatable Frontiers of Cardiovascular Risk

It's time to increase testing for this major cardiovascular risk factor in advance of new therapies

Lipoproteins

Novel siRNA Reduces Lipoprotein(a) by More Than 90% for 48 Weeks

Undetectable levels achieved for nearly nine months in phase 1 trial

pill tablets of various colors

Dietary Supplements Don’t Stack Up to Low-Dose Statin Therapy for LDL-C Reduction

Randomized controlled study undercuts unsubstantiated ‘heart health’ claims

22-HVI-2769711_lipoprotein(a)_650x450

Novel siRNA Therapy Lowers Elevated Plasma Lipoprotein(a) in Phase 1 APOLLO Trial

Targeted mRNA blocking could be first effective approach specific to this cardiovascular risk factor

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