Data from 15 centers in the U.S. and Europe indicate that immunosuppressive therapy should be used more frequently in patients with myelodysplastic syndromes.
A multicenter team studied the safety of immunotherapy atezolizumab in patients with myelodysplastic syndrome who had either failed or never received conventional HMA therapy.
The list of cancer immunotherapy drugs is growing, along with immune-related adverse events (IRAEs). ACR 2018 offers several sessions to update rheumatology providers on this fast-developing topic.
Immunotherapy hasn’t benefited breast cancer patients — yet. Breast medical oncologist Megan Kruse, MD, explains how that may be changing.
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Investigating tumor mutational burden, specific driver mutations, immune-related RNA expression data and various clinicopathologic features from 479 tumors to find correlations with clinical characteristics and outcomes.
By now most rheumatologists are aware that checkpoint inhibitors are capable of unleashing a wide array of autoimmune and autoinflammatory adverse events within virtually every organ system. These complications have posed new challenges to all practitioners.
Individuals with clinically unapparent HBV and concomitant immune-mediated inflammatory diseases (IMIDs) (e.g., rheumatoid arthritis, psoriasis, inflammatory bowel disease and others) are particularly vulnerable to HBV reactivation when immunosuppressed.
A dynamic interaction between the peripheral immune system and the CNS is fueling enthusiasm for immunotherapeutic approaches to glioblastoma. Here’s a look at a range of trials of various strategies.
Immunological therapy is changing how oncologists treat cancers—not just hematologic malignancies, but also solid tumors.
Patients with metastatic or locally advanced urothelial cancer treated with chemotherapy, or those who are not candidates for cisplatin-based chemotherapy, may have hope in newer immunotherapeutic agent pembrolizumab.