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Novel insights from a postmortem study combining imaging, pathology and clinical perspectives
GFAP elevation may signal increased risk of progressive regional atrophy, cognitive decline
A focus on biological processes should improve both research and management
Neuropsychological, serum and MRI measures improve over time relative to active fighters
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New insights into shared inflammatory pathways and immune responses
Longitudinal study implicates a specific pathway in mild cognitive impairment stage
Researchers pair postmortem MRI with histopathology to explore thalamic atrophy
Finding suggests need for multifront therapeutic approach
New R35 funding will help pursue neuroprotective therapies
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