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Novel insights from a postmortem study combining imaging, pathology and clinical perspectives
GFAP elevation may signal increased risk of progressive regional atrophy, cognitive decline
A focus on biological processes should improve both research and management
Neuropsychological, serum and MRI measures improve over time relative to active fighters
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New insights into shared inflammatory pathways and immune responses
Longitudinal study implicates a specific pathway in mild cognitive impairment stage
Researchers pair postmortem MRI with histopathology to explore thalamic atrophy
Finding suggests need for multifront therapeutic approach
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