Contrasting results raise interesting questions about these diseases and highlight the importance of continued research in vasculitis.
Search Results for: abatacept
ABROGATE Trial Launched to Assess Abatacept for Nonsevere Granulomatosis with Polyangiitis
Despite advances in treating granulomatosis with polyangiitis (GPA), 50 to 70 percent of patients experience relapses after remission induction. Reduction of those relapses is a need that this study aims to meet.
Improvement Seen in Use of Abatacept in Nonsevere Relapsing Granulomatosis with Polyangiitis (Wegener’s)
In a small study of patients with nonsevere relapsing GPA, abatacept was well tolerated and was associated with a high frequency of disease remission and prednisone discontinuation.
COVID-19 Vaccines in Patients with Immune-Mediated Inflammatory Diseases
A member of the ACR COVID-19 Vaccine Clinical Guidance Task Force provides an update on the latest data.
Balancing the Benefits of Biologic Therapy for Autoimmune Disease Against the Risks of Mycobacterial Infections
Tumor necrosis factor-α inhibitors (TNFis) have transformed care for rheumatoid arthritis and other autoimmune diseases, but they also are associated with higher risks of serious and opportunistic infections than traditional disease-modifying antirheumatic drugs. In this article, Cassandra Calabrese, DO, discusses balancing the benefits of biologic therapies with the risks of infection.
Rheumatology-Oncology: Understanding Autoimmunity Through the Lens of Checkpoint Inhibitor Biology
Checkpoint inhibitors are effective cancer treatments yet are linked with a wide array of autoimmune diseases. Exploring checkpoint biology may add new insights on the pathogenesis and treatment of autoimmunity.
A New Biomarker for Disease Activity in Large Vessel Vasculitis
Current biomarkers used in giant cell arteritis (GCA) and Takayasu arteritis (TAK) are insufficiently specific for assessing disease activity. This study assessed whether S100 proteins were associated with disease activity in GCA and TAK.
Positron Emission Tomography in Large Vessel Vasculitis
The role of PET imaging in patients with large vessel vasculitis is not yet clearly defined.
MPA, GPA, EGPA, Oh My! Vasculitis CME for the Fearless Clinician
No need to fear the vasculitides with this online, on-demand, complimentary CME.
60-Second Sound-off: How Biologics Fundamentally Changed Clinical Immunology (Video)
Leonard H. Calabrese, DO, Director of the R.J. Fasenmyer Center for Clinical Immunology, explains in less than 60 seconds why rheumatologists are no longer satisfied with “small outcomes” for their patients.