A multidisciplinary team seeks to elucidate the underlying cytokine biology of Susac syndrome. In this article, rheumatologists discuss why they hope to identify new therapeutic targets for the rare condition.
Search Results for: susac syndrome
Uveitis Referral Leads to Diagnosis of Susac Syndrome
A 28-year-old woman presents with a constellation of symptoms that point to an immune-mediated, occlusive microvascular endotheliopathy. In this article, retina and uveitis specialist, Sumit Sharma, MD, describes the astute workup that leads to the correct diagnosis.
Susac Syndrome May Be Associated with Gastrointestinal Compromise
Susac Syndrome primarily affects the brain, retina and inner ear. But it’s possible that it will sometimes affect other organs, including muscle or the GI tract.
Susac Syndrome: Pooling Efforts at the Global Level Against a Newly Recognized Disease
An international collaborative study and disease registry are among an array of efforts led out of Cleveland Clinic to better understand and manage this rare autoimmune disease.
Advances in the Diagnosis of Central Nervous System Vasculitis
Arriving at a diagnosis of CNS-V is fraught with challenges. There is no classic presentation, the condition has several mimics, brain tissue is inaccessible and there is no disease-specific test. However, advances in neuroimaging and next-generation sequencing have added formidably to our knowledge of CNS-V.
Expanding the Retinal Imaging Field with Ultra-Widefield Technology
Cole Eye Institute ophthalmologists are seeking to understand how an enhanced retinal imaging technology, known as ultra-widefield imaging, can clarify how to best manage patients based on the degree of ischemic burden.
Can Patient-Reported Measures Aid Assessment of Disease Activity in Inflammatory Eye Disease?
For patients, visible symptoms of uveitis correlate with perceptions of worse physical health, according to a recent study. Ophthalmologist Sunil Srivastava, MD, and rheumatologists Rula Hajj-Ali, Joshua Hedrick, MD, explain the relationship between patient reported outcomes measures and disease activity in inflammatory eye disease.
Inflammatory Eye Disease in Patients with Hidradenitis Suppurativa
Clinicians should be aware of a possible association between HS and inflammatory eye disease, perhaps arising from an immune dysregulation phenomenon similar to that which links Crohn’s and HS.
Preserving Vision after Lupus Retinal Vasculitis Diagnosis
Aggressive measures are called for in cases of systemic lupus erythematosus retinal vasculitis. Without accurate diagnosis and treatments, stakes are high, including the risk of major vision loss.