May 10, 2021

Crossing Boundaries: An Orthopaedic Oncologist and Thoracic Surgeon Team Up on 2 Complex Chondrosarcoma Cases

Complex chondrosarcoma cases pose challenges, utilize partnership

21-ORT-2113558-Thoracic-Oncology-and-Orthopaedics-CQD

As an orthopaedic oncologist, Nathan Mesko, MD, partners with specialists across the enterprise, “crossing the usual boundaries of extremity surgery,” he says.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

This was true recently when Dr. Mesko partnered with thoracic surgeon Daniel Raymond, MD, of Cleveland Clinic’s Department of Thoracic and Cardiovascular Surgery, on two separate chondrosarcoma cases. Chondrosarcoma, a rare and malignant primary bone sarcoma that develops in cartilage cells, can be difficult to diagnose and treat. Tumor resection is the preferred management of the disease.

Case 1: Chondrosarcoma of the manubrium

The first case involved a man in his mid-20s, who presented with chondrosarcoma of the manubrium, the top part of the breastbone. It was a low-grade tumor, Dr. Mesko explains. The goal was to remove it cleanly, sparing as much anatomy as possible.

By working with industry partners, the team was able to create a custom cutting jig design, allowing them to gain accurate margins while sparing as much bone as possible for reconstruction purposes. Next, they reconstructed the defect, utilizing orthopedic techniques, involving screws and bone cement, to create a rebar and wet concrete-type reconstruction of the manubrium. This approach enabled the patient’s full function immediately.

Case 2: Chondrosarcoma of the sternum

The second case involved a man in his 70s, who had undergone multiple resections of sternal chondrosarcoma. Dr. Mesko and his team were tasked with removing about 70% of his sternum bone and a portion of the medial clavicle while navigating precarious anatomic architecture behind the sternum.

“With such a large defect, leaving the defect open would predispose the patient to direct trauma to his heart and progressive spinal deformity, both of which, ultimately, would be life-threatening,” he says.

Advertisement

The team created a 3D model to prepare for the resection by working with the local bone bank and industry partners. They used measurements from the anticipated defect in the chest and identified a matching femoral donor bone allograft, utilizing a cadaveric femur to reconstruct this defect.

Because of the limited bone fixation, the team utilized multiple orthopaedic principles to help gain fixation, including plating, long cannulated screws and suspension with strong suture material. The graft was also supplemented with bone cement to increase its strength and all of the junctions were bone grafted.


No ‘lone cowboys’ in complex cancer surgery

Dr. Mesko reinforces the importance of multidisciplinary environments that facilitate collaboration between seemingly disparate specialties. “There is no such thing as lone cowboys in the world of complex cancer surgery,” he remarks.

Advertisement

“My partners are my lifeline and my fuel, and being able to tell a patient that we got your cancer out and the surgery went off without a hitch can only occur when you have partners that are united and invested in the common goal.”

Related Articles

20-ORI-1943011-CQD-Bridging-the-Gap-Hero
October 6, 2020
Bridging the Gap: Solutions for Intercalary Long Bone Reconstruction

Why multidisciplinary surgical and cancer teams are essential

18-ORT-1081-Nystrom-Hero-Image-650x450pxl
March 7, 2018
When Sarcoma is Suspected

How to manage cases from early symptoms to referral: A guide for PCPs

17-ORT-1274-Ilaslan-Hero-Image-650x450pxl
March 5, 2018
Radiation-Induced Focal Cortical Necrosis of the Femur after Sarcoma Treatment Presents As Lytic Lesions (Slideshow)

Two unusual sarcoma cases where necrosis develops in cortical versus medullary bone

17-ORT-1244-Nystrom-Hero-Image-650x450pxl
December 14, 2017
Multidisciplinary Care in Musculoskeletal Oncology: A Case Study

Sarcoma Program shows we’re better together

14-ORT-978-Joyce-Hero-Image-690x380pxl
February 19, 2015
Fortunately, Enchondroma Lesions Are Rarely Malignant

But their discovery still warrants vigilant follow up

Leitman-Joyce-Hero-Image-690x380pxl
January 14, 2015
Giant Cell Tumor of Bone: Benign but Still Worthy of Vigilance

Follow-up after tumor removal is essential

Blue illustration of knee with torn ACL in red
February 29, 2024
Aspiration and Corticosteroid Injection Are Safe After ACL Injury

Study reports zero infections in nearly 300 patients

Swollen knee with scar
February 26, 2024
Is Joint Inflammation and Pain After Total Knee Arthroplasty an Infection or Gout?

How to diagnose and treat crystalline arthropathy after knee replacement

Ad