Conventional guidelines discourage children and adolescents with congenital long QT syndrome (LQTS) from participating in most competitive sports. Due to risk of life-threatening cardiac arrhythmias, youths with LQTS have been restricted to six low-intensity sports: billiards, bowling, cricket, curling, golf and riflery.
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
But now a new study in the debut issue of JACC: Clinical Electrophysiology reveals that pediatric patients with LQTS may be able to tolerate a wider range of competitive and recreational activities.
“Re-examining participation rules is important because the physiologic benefits of exercise at all ages have been emphasized repeatedly and promoted as a national public health priority,” says Peter Aziz, MD, lead author of the study and director of Cleveland Clinic Children’s Inherited Arrhythmia Clinic. “The enhanced self-confidence, sense of psychological, physical and social well-being, and improved overall quality of life that sports participation brings to children and adolescents is equally important.”
In the retrospective study, Dr. Aziz and a team of researchers examined the prevalence and outcomes of sports participation by patients with LQTS. They reviewed records of 212 patients, ages four to 21, referred to Children’s Hospital of Philadelphia’s Pediatric Arrhythmia Clinic between 1998 and 2013.
(Dr. Aziz completed pediatric cardiology and electrophysiology fellowships at Children’s Hospital of Philadelphia before joining Cleveland Clinic Children’s in 2011. While there, he began studying pediatric patients with LQTS under funding from a National Institutes of Health grant.)
Of the cohort, 103 patients participated in sports — 26 competitively and 77 recreationally. All were treated with daily beta blockers — standard therapy for preventing LQTS symptoms — although two patients did not consistently comply with the therapy.
The researchers followed patients for an average of seven years, for a total of 755 patient-years of follow-up. During that time, treatment-compliant patients recorded no cardiac events (e.g., syncope, documented arrhythmia, cardiac arrest) and no deaths while participating in sports. Two patients recorded appropriate implantable cardioverter defibrillator (ICD) shocks, but they were not related to sports participation.
“Given the changing diagnostic trends, it may be clinically beneficial to re-examine sports recommendations that were made based on data from an earlier era,” Dr. Aziz concludes in light of these results.
At the same time, he notes that the study has several limitations, including:
The authors note that physical activity is not without risk for patients with LQTS. But limiting or avoiding activity is not the only way to minimize risk, Dr. Aziz points out. Other safeguards include: