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High composite score in myectomy specimens signals worse prognosis
Avoidance of septal reduction therapy continues while LVEF dysfunction remains infrequent
Large single-center series demonstrates safety and efficacy for extending procedure
Prospective SPIRIT-HCM trial demonstrates broad gains over 12-month follow-up
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The procedure is safe, but prepare for AF recurrence rates approaching 50%
Expert insights on managing HCM when debulking isn’t an option
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