June 29, 2016

What’s the Risk of Adding Aortic Replacement to Cardiac Surgery? (Video)

Answering a key question as multicomponent operations proliferate

Dr. Roselli

Experienced cardiovascular surgery centers are seeing more and more patients who require multicomponent operations involving their valves, coronary arteries, arrhythmias and more.

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This includes many patients whose clinical picture includes a dilated ascending aorta or an aortic aneurysm associated with these other problems, prompting the question: Does adding aortic replacement to cardiac operations increase surgical risk?

To address this question, a team of cardiothoracic surgeons including Eric E. Roselli, MD, analyzed a series of 14,294 patients undergoing elective cardiac surgery at Cleveland Clinic over a recent five-year period, including 1,677 whose operations included aortic replacement.

Dr. Roselli presented their findings at the recent annual meeting of the American Association for Thoracic Surgery in Baltimore. In this video, he briefly explains the three propensity score matching analyses the team conducted to answer the question, and he shares their findings on the safety and advisability of including aortic replacement in multicomponent operations.

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“When we compared those similar groups, we found that there was no difference in death or several of the other complications, but there was a slightly increased risk of stroke in the patients who had aorta replacement, about two-and-a-half percent versus one-and-a-half percent… We wanted to look further at why we thought that stroke risk might be higher in that group of patients undergoing aortic surgery because we know this does involve a complex population of patients… We did another propensity analysis… We broke [patients] up into those who had circulatory arrest… and sure enough we found that the half of those groups who had the circulatory arrest, the risk of death and stroke was a little bit higher. Still well under 5 percent, but nowhere near these remarkable results of 1 percent or less in the other group of patients…”

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