Cornea Update

The latest in cornea treatments, news and disease care from Cleveland Clinic

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Comprehensive Cornea Care, Advancing Tomorrow’s Breakthroughs

William Dupps, Jr., MD, PhD

Dr. William Dupps, Jr.

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The Cole Eye Institute’s cornea service is among the nation’s top academic and clinical services dedicated to treating diseases of the cornea and anterior segment. Our institute was among the first centers to perform Descemet’s stripping automated endothelial keratoplasty (DSAEK), a selective procedure for endothelial diseases such as bullous keratopathy and Fuchs dystrophy that has revolutionized corneal transplantation through greater safety, faster visual recovery and more favorable refractive outcomes. Since 2005, nearly a thousand Cole Eye Institute patients have benefited from technical advances in DSAEK pioneered by our surgeons. (continued below)

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Researchers Developing 3D Patient Specific Model of Corneal Properties
NIH-funded project could aid keratoconus detection, refractive surgical screening
William J. Dupps, Jr., MD, PhD, Cleveland Clinic Cole Eye Institute cornea surgeon

Cornea Transplants: DSAEK Method Superior to PK
Benefits include more rapid return of visual acuity
William J. Dupps, Jr., MD, PhD, Cleveland Clinic Cole Eye Institute cornea surgeon

Case Study: Advanced Diagnostics Help Resolve Microsporidial Keratitis
Electron microscopy leads to the resolution of a prolonged case of microsporidial keratitis
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Contact Lens Mediated Acanthamoeba Harms Vision
Rare infection easily misdiagnosed, delaying treatment
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(continued) Our team provides comprehensive care for corneal disease, including complex corneal transplantation, advanced dry eye treatment, refractive surgery options for patients who are not candidates for LASIK or PRK, and treatment of vision-threatening infections. Our surgeons recently began performing Descemet membrane endothelial keratoplasty (DMEK), a more selective procedure for endothelial dysfunction that may offer visual advantages over DSAEK in certain patients. For a decade, our cornea service has offered the Boston Keratoprosthesis for cases of corneal blindness where traditional transplantation offers little hope, and our commitment to serving these patients will be expanded this fall with the addition of a dedicated ocular surface disease/high-risk corneal transplant specialist.

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Cole Eye Institute patients have benefited from technical advances in DSAEK pioneered by our surgeons.

One of our core missions is advancing science that drives the next breakthroughs in therapy. Our team includes leading NIH-funded investigators in corneal wound healing, corneal immunology and infection, and corneal biomechanics and simulation-based therapy. Our corneal surgeons have the world’s most extensive experience in intraperative OCT-guided surgery and are pioneering the use of this exciting technology for enhancing intraoperative visualization and patient outcomes. Access to clinical trials, including a much-anticipated clinical trial of collagen crosslinking for keratoconus, is a distinctive feature of our care model.

For more information, contact Dr. William J. Dupps, Jr. at duppsw@ccf.org.

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