Don’t Miss These Cole Eye Institute Presentations at ARVO 2019

This year’s Association for Research in Vision and Ophthalmology (ARVO) annual meeting is almost here, and Cleveland Clinic Cole Eye Institute researchers are looking forward to sharing their research progress with you.

If you’re traveling to Vancouver for ARVO 2019 (April 28-May 2), make room in your itinerary for our staff’s presentations and poster sessions. See the schedule below.

In addition, Cole Eye Institute Chair Daniel F. Martin, MD, invites colleagues to meet our presenters for lively discussions at the Institute’s booth (#713) in the Exhibit Hall. Here’s the complete booth schedule.

Paper Sessions

Sunday, April 28, 2019

4 – 4:15 p.m. / East 1 / Presentation 960

Hot Topic

Proteomics of Metastatic and Non-Metastatic Uveal Melanoma

John W. Crabb, Jack S. Crabb, Geeng-Fu Jang, Belinda Willard, Bo Hu, Helen Kalirai, Arun D. Singh, Sarah E. Coupland

Monday, April 29, 2019

11:30 – 11:45 a.m. / East 8&15 / Presentation 1710

Clinical and Imaging Outcomes of Patients with Retinal Vasculitis

Salam Bachour, Parisa Emami Naeini, Sumit Sharma, Kimberly Baynes, Arthi Venkat, Careen Lowder, Sunil K. Srivastava

11:30 – 11:45 a.m. / East 11/12 / Presentation 1716

Oxidative Stress-related Degeneration in RPE (Retinal Pigmented Epithelium) and Retina: Role of DJ-1 and Aging
Vera L. Bonilha, Mala Upadhyay

Tuesday, April 30, 2019

9 – 9:15 a.m. / East Ballroom B / Presentation 2804

Evaluation of Quantitative Ultra-widefield Fluorescein Angiography Metrics and Diabetic Macular Edema Features

Alice C. Jiang, Sunil K. Srivastava, Joseph Boss, Sumit Sharma, Jamie L. Reese, Justis P. Ehlers

1 – 1:15 p.m. / West 221-222 / Presentation 3311

Comprehensive Visual and Mobility Training in Argus II Patients Using Computer-assisted Rehabilitation System

Meghan J. DeBenedictis, Sara Davidson, Matthew Streicher, Anson Rosenfeldt, Jay Albers, Alex Yuan, Aleksandra Rachitskaya

4 – 4:15 p.m. / Room East 11/12 / Presentation 3851

Secretion of FGF-2 by the Retinal Pigment Epithelium Contributes to Hyaluronan Deposition in Sorsby’s Fundus Dystrophy

Alyson Wolk, Jian Qi, Alecia Cutler, Mariya Ali, Brent Bell, Valbona Cali, Heidi Stoehr, Ronald Midura, Vincent Hascall, Bela Anand-Apte

Wednesday, May 1, 2019

11 – 11:15 a.m. / West 211 / Presentation 4781

3-D Assessment of Corneal Crosslinking with Phase-decorrelation OCT

Brecken Blackburn, John Murray, Matthew Ford, Michael Jenkins, William Dupps, Andrew Rollins

1 – 1:15 p.m. / West 221/222 / Presentation 3311
Comprehensive Visual and Mobility Training in Argus II Patients Using Computer-assisted Rehabilitation System

Meghan J. DeBenedictis, Sara Davidson, Matthew Streicher, Anson Rosenfeldt, Jay Alberts, Alex Yuan, Aleksandra Rachitskaya

3 – 3:15 p.m. / East Ballroom B / Presentation 5188

Higher-order Optical Coherence Tomography (OCT) Fluid Burden Assessment: Analysis from the OSPREY Extended Phase

Atsuro Uchida, Julie Clark, Sunil Srivastava, Natalia Figueiredo, Amy Babiuch, Katherine Talcott, Leina Lunasco, Thuy Le, Alison Rogozinski, Jamie Reese, Justis Ehlers

3:45 – 4 p.m. / Harbour Ballroom / Presentation 5251

Descemet’s Basement Membrane Modulation of Corneal Fibrosis

Steven Wilson, Carla Medeiros, Paramananda Saikia, Rodrigo de Oliveira, Luciana Lassance, Marcony Santhiago

4:30 – 4:45 p.m. / East Ballroom B / Presentation 5194

Visual and Expanded Anatomical Outcomes for Brolucizumab Versus Aflibercept in Patients with Neovascular AMD: 96-week Data from HAWK and HARRIER

Rishi P. Singh, Charles Clifton Wykoff, Ramin Tadayoni, Yuichiro Ogura, Adrian H C. Koh, Frank G. Holz, Robin Hamilton, David Tanzer, Georges Weissgerber, Jahangir Alam, Pravin U. Dugel

4:30 – 4:45 p.m. / Harbour Ballroom / Presentation 5254

Proteome of Keratocyte-derived Versus Bone Marrow-derived Myofibroblasts. Are They Different?

Paramananda Saikia, Madison Juszczak, Luciana Dibbin, Rodrigo Oliveira, Carla Medeiros, Belinda Willard, Jang Geeng-Fu, Jack Crabb, John Crabb, Steven Wilson

Thursday, May 2, 2019

11 – 11:15 a.m. / East 11-12 / Abstract 6406 / Presentation 6406

Müller Glia Proliferation and Cone Regeneration is Triggered by Acute Damage but not Progressive Photoreceptor Degeneration in Zebrafish CEP290-/-Mutants

Joseph Fogerty, Ping Song, Lauren T. Cianciolo, Rose DiCicco, Brian D. Perkins

Poster Sessions

Sunday, April 28, 2019

8 – 9:45 a.m. / West Exhibition Hall / Abstract 110 / Posterboard A0291

Hot Topic

Macular Atrophy Affecting Visual Outcomes in Patients Undergoing Anti-VEGF Treatment

Weilin Song, Nathaniel B. Rieveschl, Ang Li, Thais Conti, Grant L. Hom, Rishi P. Singh

8 – 9:45 a.m. / West Exhibition Hall / Abstract 175 / Posterboard A0584

The Prospective Imaging Quantification of Ocular Inflammation (IQI) Study

Sunil Srivastava, Kimberly Baynes, Sumit Sharma, Arthi Venkat, Careen Lowder

8 – 9:45 a.m. / West Exhibition Hall / Abstract 213 / Posterboard A0622

Response to Patching in Amblyopic Patients With and Without Fusion Maldevelopment Nystagmus

Fatema Firoz Ghasif, Aasef Shaikh

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1655 / Posterboard B0292

Müller Cell HIF-2 is Not Required for Protection Against Oxygen-induced Retinopathy by Prolyl Hydroxylase Inhibition

George Hoppe, Youstina Bolok, Leah McCollum, Charandeep Singh, Jonathan Sears

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1667 / Posterboard B0304

Hot Topic

Lactate Transporters are Essential for Maintaining Function in Rod but Not Cone Photoreceptor Cells

John Han, Junzo Kinoshita, Jianhai Du, Sara Bisetto, Brent A. Bell, Romana Nowak, Neal S. Peachey, Nancy J. Philp

1 – 2:45 p.m. / West Exhibition Hall / Abstract 747 / Posterboard B0225

Hot Topic

Validation of Choroid from Uveal Melanoma Eyes as Control Tissue for Proteomic Studies

Geeng-Fu Jang, Jack Crabb, Bo Hu, Belinda Willard, Helen Kalirai, Arun Singh, Sarah Coupland, John Crabb

1 – 2:45 p.m. / West Exhibition Hall / Abstract 486 / Posterboard A0477

Intraoperative Optical Coherence Tomography During Cataract Surgery in the DISCOVER Study

Rachel C. Chen, Michael E. Millstein, Sunil K. Srivastava, Jamie L. Reese, Justis P. Ehlers

1 – 2:45 p.m. / West Exhibition Hall / Abstract 523 / Posterboard A0656

Saccades in Parkinson’s Disease: Hypometric, Slow, or Maladaptive?

Aasef Shaiki, Fatema Firoz Ghasia

3 – 4:45 p.m. / West Exhibition Hall / Abstract 1144 / Posterboard A0158

Incidence and Features of Geographic Atrophy in Fellow Eyes in the Comparison of Age-related Macular Degeneration Treatment Trials (CATT)

Delu Song, Gui-Shuang Ying, Juan Grunwald, Ebenezer Daniel, Maureen Maguire, Yafeng Li, Daniel Martin

3 – 4:45 p.m. / West Exhibition Hall / Abstract 1198 / Posterboard A0212

Hot Topic

Visual Outcomes Following Cataract Surgery in Neovascular Age-Related Macular Degeneration Patients in Routine Clinical Practice

Andrew Chen, Alexander Haueisen, Chandruganesh Rasendran, Grant Hom, Thais Conti, Felipe Conti, Katherine Talcott, Rishi Singh

3 – 4:45 p.m. / West Exhibition Hall / Abstract 1301 / Posterboard A0546

Hot Topic

Automated Analysis of Anterior Chamber Inflammation by Spectral-Domain Optical Coherence Tomography in Cataract Surgery Patients

Sumit Sharma, Richard Gans, Kimberly Baynes, Emily Fisher, Peter Kaiser, Arthi Venkat, Careen Lowder, Sunil Srivastava

4 – 4:45 p.m. / West Exhibition Hall / Abstract 2621 / Posterboard B0152

Hot Topic

Diabetic Macular Edema Treated with Intravitreal Aflibercept Injection after Treatment with Other Anti-VEGF Agents (SWAP-TWO Study) – 12-month Interim Analysis

Cyrus Golshani, Thais Conti, Felipe Conti, Fabiana Q. Silva, Aleksandra Rachitskaya, Alex Yuan, Andrew Schachat, Peter K. Kaiser, Rishi P. Sing, Amy Babiuch

4 – 4:45 p.m. / West Exhibition Hall / Abstract 2717 / Posterboard B0248

Elucidating Sexual Dimorphism in the Retina of Mice with Type 1 Diabetes

Shiming Luo, Jack Crabb, Mariya Ali, Alyson Wolk, Geeng-Fu Jang, Belinda Willard, John Crabb, Bela Anand-Apte

Monday, April 29, 2019

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1437 / Posterboard A0121

Hot Topic

Predicting Tolerance to Extended Interval Dosing in Diabetic Macular Edema and Retinal Vein Occlusion via Subvisual Feature Assessment in Ultra-wide-field Angiography: Preliminary Findings in the PERMEATE Study

Azam Moosavi, Natalia Figueiredo, Prateek Prasanna, Sunil K. Srivastava, Ming Hu, Sumit Sharma, Jamie L. Reese, Justis P. Ehlers, Anant Madabhushi

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1552/ Posterboard A0312

Comparison of Wide-field Confocal Laser Scanning Ophthalmoscopy and Broad Line Fundus Imaging in Retinal Disease in Routine Clinical Practice

Thais Conti, Grant Hom, Netan Choudhry, Rishi Singh

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1572 / Posterboard A0332

Detection of Retinoschisis and Retinal Detachment by Wide-field Fundus Autofluorescence Imaging

Author Block: Jessica Cao, Thais Conti, Grant Hom, Amy Babiuch, Rishi P. Singh

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1575 / Posterboard A0335

Automated Quantification of Vascular Leakage in Ultra-Wide-field Fluorescein Angiography in Patients Treated with Fluocinolone Acetonide Implant 0.59mg

Arjun Sood, Sumit Sharma, Kimberly Baynes, Emily Fisher, Naveen Karthik, Jennifer Welsh, Ashley Balascoe, Careen Lowder, Sunil K. Srivastava

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1667 / Posterboard B0304

Lactate Transporters Are Essential for Maintaining Function in Rod but Not Cone Photoreceptor Cells

John Yeong Se Han, Junzo Kinoshita, Jianhai Du, Sara Bisetto, Brent A. Bell, Romana Nowak, Neal S. Peachey, Nancy J. Philp

8:15 – 10 a.m. / West Exhibition Hall / Abstract 1694 / Posterboard B0331

Hot Topic

Catechin Protects ARPE19 Cells Under Blue Light Exposure from Oxidative Stress

Minzhong Yu, Maojing Yang, Xiufeng Zhong

11:15 am – 12 p.m. / West Exhibition Hall / Abstract 1854 / Posterboard A0245

Long-Term Longitudinal Ellipsoid Zone Mapping on Spectral Domain OCT in Eyes with Hydroxychloroquine Use to Evaluate for Subclinical Outer Retinal Alterations: A Possible Early Marker for Toxicity

Katherine Talcott, Atsuro Uchida, Ming Hu, Obinna Ugwuegbu, Sunil Srivastava, Rishi Singh, Stephanie Kaiser, Natalia Figueiredo, Alison Rogozinski, Thuy Le, Leina Lunasco, Jamie Reese, Justis Ehlers

11:15 a.m. – 1 p.m. / West Exhibition Hall / Abstract 1872 / Posterboard A0263

Comparative Evaluation of Surgical Outcomes of Intraoperative OCT-guided and Conventional Surgery for Epiretinal Membrane Peeling from the DISCOVER Study

Alison Rogozinski, Tisileli Tuifua, Sunil K. Srivastava, Peter K. Kaiser, Ming Hu, Aleksandra Rachitskaya, Sumit Sharma, Rishi P. Singh, Thuy K. Le, Leina Moani Lehua Lunasco, Francesca Fabe, Carmen Calabrise, Sarah Biehl, Sruthi Srinivasan, Jamie L. Reese, Justis P. Ehlers

11:15 a.m. – 1 p.m. / West Exhibition Hall / Abstract 1883 / Posterboard A0274

Analysis of Longitudinal Ellipsoid Zone Features Following Intraoperative OCT-Assisted Macular Hole Repair and the Association with Functional Outcomes from the DISCOVER Study

Thuy K. Le, Philina Yee, Sunil K. Srivastava, Atsuro Uchida, Ming Hu, Alison Rogozinski, Sarah Biehl, Sruthi Srinivasan, Francesca Fabe, Aleksandra Rachitskaya, Sumit Sharma, Jamie L. Reese, Justis P. Ehlers

11:15 a.m. – 1 p.m. / West Exhibition Hall / Abstract 1884 / Posterboard A0275

Quantitative Ellipsoid Zone Mapping and Integrity Assessment on Optical Coherence Tomography in the VISTA DME Study

Leina Lunasco, Atsuro Uchida, Sunil Srivastava, Natalia Figueiredo, Andrea Gibson, Kim Reed, Jamie Reese, Justis Ehlers

11:15 a.m. – 1 p.m. / West Exhibition Hall / Abstract 1900 / Posterboard A0291

Automated Analysis of Anterior Chamber Inflammation by Spectral-Domain Optical Coherence Tomography in Pediatric Uveitis Patients

Peter M. Kaiser, Sumit Sharma, Kimberly Baynes, Emily Fisher, Arthi Venkat, Careen Lowder, Sunil K. Srivastava

11:15 a.m. – 1 p.m. / West Exhibition Hall / Abstract 1913 / Posterboard A0438

Alterations in Microvilli on the Surface of Retinal Pigment Epithelial (RPE) Cells in Sorsby’s Fundus Dystrophy

Mariya Ali, Jian Hua Qi, Alyson Wolk, Alecia Cutler, Heidi Stohr, Courtney Hershberger, Gautam Mahajan, Chandrasekhar Kothapalli, Bela Anand-Apte

4 – 5:45 p.m. / West Exhibition Hall / Abstract 2621 / Posterboard B0152

Diabetic Macular Edema Treated with Intravitreal Aflibercept Injection after Treatment with Other Anti-VEGF Agents (SWAP-TWO Study) – 12-month Interim Analysis

Cyrus Golshani, Thais Conti, Felipe Conti, Fabiana Silva, Aleksandra Rachitskaya, Alex Yuan, Andrew Schachat, Peter Kaiser, Rishi Singh, Amy Babiuch

4 – 5:45 p.m. / West Exhibition Hall / Abstract 2689 / Posterboard B0220

A Novel Zebrafish Model of Insulin-induced Blood-retinal Barrier Breakdown

Lana Pollock, Jing Xie, Brent A. Bell, Bela Anand-Apte

4 – 5:45 p.m. / West Exhibition Hall / Abstract 2717 / Posterboard B0248

Elucidating Sexual Dimorphism in the Retina of Mice with Type 1 Diabetes

Shiming Luo, Jack S Crabb, Mariya Ali, Alyson Wolk, Geeng-Fu Jang, Belinda Willard, John W Crabb, Bela Anand-Apte

Tuesday, April 30, 2019

8:45 – 10:30 a.m. / West Exhibition Hall / Abstract 2947 / Posterboard A0230

Novel Mutation in CTNNB1 Causing Familial Exudative Vitreoretinopathy and Microcephaly

Razek Georges Coussa, Yue Zhao, Meghan DeBenedictis, Allison Babiuch, Jonathan Sears, Elias Traboulsi

11:45 a.m. – 1:30 p.m. / West Exhibition Hall / Abstract 3462 / Posterboard A0305

Hot Topic

Flavoprotien Fluorescence is a Marker for AMD Progression

Jessica Hsueh, Raffaele Raimondi, Grant Hom, Thais Conti, Rishi P. Singh

11:45 a.m. – 1:30 p.m. / West Exhibition Hall / Abstract 3507 / Posterboard A0548

Sensitivity and Predictive Value of Radiography and ACE Levels in the Diagnosis of Sarcoid Uveitis

Jawad Arshad, Daniel Culver, Kimberly Baynes, Sumit Sharma, Sunil Srivastava

11:45 a.m. – 1:30 p.m. / West Exhibition Hall / Abstract 3532 / Posterboard A0573

Local Therapy for Cancer Immunotherapy-Associated Uveitis

Arthi Venkat, Sruthi Arepalli, Sumit Sharma, Naveen Karthik, Careen Lowder, Sunil Srivastava

11:45 a.m. – 1:30 p.m. / West Exhibition Hall / Abstract 3729 / Posterboard B0276

Deficiencies in United States Ophthalmology Residents’ Case Logging of Minimally Invasive Glaucoma Surgeries (MIGS)

Mary Qiu, Jeffrey Goshe

11:45 a.m. – 1:30 p.m. / West Exhibition Hall / Abstract 3739 / Posterboard B0286

Minimally Invasive Glaucoma Surgery Efficacy in Uveitic and Steroid-induced Glaucoma

Robert Purgert, Careen Lowder, Jonathan Eisengart

2:45 – 4:30 p.m. / West Exhibition Hall / Abstract 3983 / Posterboard A0482

TULP1 Missense Mutations Cause Variable Retinal Phenotypes

Satyabrata Sinha, Gayle Pauer, Neal S. Peachey, Stephanie A. Hagstrom

Wednesday, May 1, 2019

8:15 – 10 a.m. / West Exhibition Hall / Abstract 4304 / Posterboard A0020

Comparison of Orbital Volume in Young versus Senescent Human Skulls

Kevin Zhang, Catherine Hwang, Julian Perry

8:15 – 10 a.m. / West Exhibition Hall / Abstract 4401 / Posterboard A0292

Alcama is Expressed in Zebrafish Müller Glia Following Retinal Injury

Kristin Allan, Michael Ramos, Rose DiCicco, Alex Yuan

8:15 – 10 a.m. / West Exhibition Hall / Abstract 4571 / Posterboard A0556

Swept-source Optical Coherence Tomography Angiography Detection of Flow Abnormalities in Patients with Pulmonary Sarcoidosis

Torrey Guan, Arthi Venkat, Kimberly Baynes, Emily Fisher, Ashley Balascoe, Jennifer Welsh, Peter Kaiser, Sunil Srivastava, Sumit Sharma

8:15 – 10 a.m. / West Exhibition Hall / Abstract 4639 / Posterboard B0133

Hot Topic

A Novel Role for Cytoskeletal Keratin 6a in Regulating Acute Corneal Inflammation

Jonathan Chan, Yan Sun, Karthikeyan Bose, William Carrera, KP Connie Tam

8:15 – 10 a.m. / West Exhibition Hall / Abstract 4663 / Posterboard B0188

Laminins and Early Corneal Epithelial Basement Membrane (EBM) Regeneration

Rodrigo Carlos De Oliveira, Paramananda Saikia, Steven E. Wilson

10:15 a.m. – 12 p.m. / West Exhibition Hall / Abstract 5010 / Posterboard A0473

Eplerenone for the Treatment of Central Serous Chorioretinopathy: 3-year Clinical Experience

Daniel Petkovsek, Felipe Conti, Daniel G. Cherfan, Justis P. Ehlers, Peter K. Kaiser, Andrew Schachat, Sumit Sharma, Sunil K. Srivastava, Aleksandra Rachitskaya, Amy Babiuch, Rishi P. Singh

11:45 a.m. – 1:30 p.m. / West Exhibition Hall / Abstract 3729 / Posterboard B0276

Deficiencies in United States Ophthalmology Residents’ Case Logging of Minimally Invasive Glaucoma Surgeries (MIGS)

Mary Qiu, Jeffrey Goshe

3 – 4:45 p.m. / West Exhibition Hall / Abstract 5336 / Posterboard B0032

Hot Topic

Correlation of Quantitative Ultra-Wide-field Angiographic Metrics and Diabetic Retinopathy Severity Score Improvement Following Aflibercept Therapy in the PERMEATE Study

Natalia Albuquerque Lucena Figueiredo, Sunil K. Srivastava, Ming Hu, Jamie L. Reese, Justis P. Ehlers

3 – 4:45 p.m./ West Exhibition Hall / Abstract 5337 / Posterboard B0033

Hot Topic

Longitudinal Panretinal Leakage Index Assessment in Proliferative Diabetic Retinopathy Treated with Intravitreal Aflibercept on Ultra-Wide-field Fluorescein Angiography from the RECOVERY Study

Jenna Marie Hach, Charles Clifton Wykoff, Amy Babiuch, Natalia Albuquerque Lucena Figueiredo, Sunil K. Srivastava, Brenda Zhou, Alexander Michael Rusakevich, Alison Rogozinski, Thuy Le, Leina Lunasco, Jamie L. Reese, Justis P. Ehlers

3 – 4:45 p.m. / West Exhibition Hall / Abstract 5351 / Posterboard B0047

Non-invasive Assessment of Retinal Mitochondrial Dysfunction in Diabetic Retinopathy

Raffaele Raimondi, Grant Hom, Thais Conti, Jessica Hsueh, Rishi Singh

Thursday, May 2, 2019

8 – 9:45 a.m. / West Exhibition Hall / Abstract 5714 / Posterboard A0109

Hydroxychloroquine Toxicity Screening Using Semi-Automated Ellipsoid Zone Mapping Program

Stephanie Kaiser, Atsuro Uchida, Katherine Talcott, Ming Hu, Natalia Figueiredo, Sunil Srivastava, Obinna Ugwuegbu, Alison Rogozinski, Thuy Le, Leina Lunasco, Jamie Reese, Justis Ehlers

8 – 9:45 a.m. / West Exhibition Hall / Abstract 5802 / Posterboard A0247

Hot Topic

Evaluating Ophthalmic Surgical Efficiency through the Stellaris® Platform: The Impact of Surgeon Volume and Gauge Size on Pars Plana Vitrectomy

Naveen Karthik, Valeri Kolesnitchenko, Ronald Cummings-Kralik, Brian McCary, Sunil K. Srivastava

10:15 a.m. – 12 p.m. / West Exhibition Hall / Abstract 6695 / Posterboard B0150

The Incidence of Depression and Correlation to Visual Function in Active Uveitis Patients

Kimberly Baynes, Sumit Sharma, Emily Fisher, Ashley Balascoe, Sunil K. Srivastava

10:15 a.m. – 12 p.m. / West Exhibition Hall / Abstract 6705 / Posterboard B0160

CDCP1 as a Novel Regulator of Corneal Epithelial Wound Healing

Lingjun Zhang, Yan Beck, Ping Huang, K P Connie Tam, Feng Lin

10:15 a.m. – 12 p.m. / West Exhibition Hall / Abstract 6835 / Posterboard B0413

3D Patient-Specific Finite Element Model (FEM) of Intracorneal Ring Segment (ICRS) Implantation

Ibrahim Seven, Rafael Grytz, William Dupps