REGROUP Reassures About Endoscopic Saphenous Vein Harvesting in CABG (Video)

Large trial finds no outcomes difference from open harvesting

“A big sigh of relief for the cardiovascular community.” That’s how Cleveland Clinic cardiothoracic surgeon Faisal Bakaeen, MD, characterizes results of the REGROUP trial comparing endoscopic and open harvesting of vein grafts for coronary artery bypass graft surgery (CABG).

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Dr. Bakaeen is a leading co-author of the multicenter trial, which was published online by the New England Journal of Medicine concurrent with its presentation as a late-breaking trial at the 2018 American Heart Association Scientific Sessions in Chicago. The 1,150-patient prospective randomized investigation eased lingering concerns about the safety and efficacy of using saphenous vein grafts harvested endoscopically versus those harvested via open techniques, finding no significant difference in rates of major adverse cardiac events between the two harvesting methods.

In the five-minute video below, Dr. Bakaeen explains the rationale and context for the trial and its implications for CABG practice moving forward, including the importance of the experience of the harvester for optimal outcomes with endoscopic harvesting.