Modified-Bentall single-patch Konno enlargement (BeSPoKE) optimizes hemodynamics, facilitates future TAVR
Age and other factors figure into the choice among SAVR, TAVR, Ross, Ozaki and more
Optimally timed valve replacement depends on an expert approach to nuanced presentations
Aortic valve replacement is best option for lowering mortality in this high-risk population
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Large longitudinal study supports earlier intervention over clinical surveillance
Support for a TAVR-first approach in patients with concurrent valve and coronary disease
Five-year data demonstrate convergence of outcomes from years 1 to 5
Randomized WATCH-TAVR trial confirms safety of the combined procedures
Potential benefits include clinical guidance, TAVR outcome prediction, device testing
Sophisticated in vivo modeling can enhance device development and therapy testing
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