Researchers have shown that the long noncoding gene ANRIL is the causal gene for CAD at the locus within chromosome 9. This suggests maintaining or boosting ANRIL expression may be a viable target for future CAD therapies.
The decision to take a statin for primary prevention of coronary disease is a personal one involving the weighing of multiple factors. In many cases, calcium scoring should be part of the mix.
If calcium scoring is not used in the appropriate clinical setting, misinterpretation of the results can prompt unneeded cardiac testing. We share our approach, including illustrative case vignettes.
A novel biomarker derived from coronary CT angiography has been found to identify residual cardiovascular risk with independent and incremental value over modern risk scores and imaging measures.
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Current guidelines recommend exercise stress echo, but it can’t reliably detect significant obstructive CAD in patients with LBBB at rest. We share nuanced recommendations for alternatives.
The recent landmark trial conclusively proved the inflammatory hypothesis of atherothrombosis. But it did a good deal more. Dr. Steven Nissen explains.
A Cleveland Clinic expert advised a group called STEMI India on how to develop a system of STEMI care for their nation. The effort’s early outcome improvements are now sparking interest across the globe.