Findings from a phase IIa global trial found rituximab to be generally safe, well-tolerated and effective in the treatment of granulomatosis with polyangiitis or microscopic polyangiitis in pediatric patients.
Case Report: Long-Term Monitoring a Must for ANCA-Associated Vasculitis
Even after a long period of remission, ANCA-associated vasculitis can return with force. Long-term monitoring is key.
Nasal Reconstruction for Granulomatosis with Polyangiitis
With an osteocartilaginous L-strut technique, Cleveland Clinic’s facial reconstructive surgeons provide long-lasting and aesthetically favorable results to patients with GPA, allowing them a return to normal life.
Idiopathic Subglottic Stenosis: Misdiagnosis with Asthma Is Common
While diagnosing iSGS can be challenging, treatments for the condition have advanced in recent years.
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Recognizing Noninfectious Autoimmune Scleritis
When assessing a patient for “red-eye” with severe ocular pain, rheumatologists should have a high index of suspicion for scleritis. In this article, rheumatologist Rula Hajj-Ali, MD, discusses how to alleviate pain and prevent complications in inflammatory eye disease.
Pregnancy in Vasculitis: Issues to Consider
A 34-year-old female you have followed for granulomatosis with polyangiitis (GPA) comes to your clinic to discuss whether she is able to pursue a pregnancy. What are the key discussion points you need to have with your patient?
Granulomatosis with Polyangiitis: A Persistent Risk Factor in Recurrent VTE
The rate of VTE recurrence in patients with GPA is similar to that of first VTE recurrence in patients with cancer.
Dyspnea in a Patient with Wegener’s: How Would You Assess It?
This case study of recent dyspnea in a patient with granulomatosis with polyangiitis (Wegener’s) shows the value a multidisciplinary approach brings to vasculitis management.
Optimizing Vasculitis Management Through Multidisciplinary Care: 2 Cases, 1 Lesson
Two highly distinct case vignettes demonstrate that multidisciplinary expertise is essential to managing the acute life-threatening complications that vasculitis can pose.
ABROGATE Trial Launched to Assess Abatacept for Nonsevere Granulomatosis with Polyangiitis
Despite advances in treating granulomatosis with polyangiitis (GPA), 50 to 70 percent of patients experience relapses after remission induction. Reduction of those relapses is a need that this study aims to meet.