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Tag: hypertrophic cardiomyopathy (HCM)

histopathologic image of tissue from a hypertrophied heart

November 22, 2024/Heart, Vascular and Thoracic/Clinical Cardiology

Myocardium Histology Predicts Long-Term Outcomes of Obstructive Hypertrophic Cardiomyopathy

High composite score in myectomy specimens signals worse prognosis

November 21, 2024/Heart, Vascular and Thoracic/Clinical Cardiology

REMS Update: Mavacamten Still Effective in Treating Real-World Patients With HCM

Few patients report left ventricular dysfunction or heart failure after one year

cardiac MRI showing obstructive hypertrophic cardiomyopathy

November 20, 2024/Heart, Vascular and Thoracic/Clinical Cardiology

Final VALOR-HCM Report: At 128 Weeks, Mavacamten Sustains Gains in HCM Patients

Avoidance of septal reduction therapy continues while LVEF dysfunction remains infrequent

left ventricular apex in heart affected by hypertophic cardiomopathy

September 30, 2024/Heart, Vascular and Thoracic/Clinical Cardiology

Registry Study Identifies Hallmarks of Apical Hypertrophic Cardiomyopathy

New risk score pools factors that may predict adverse outcomes in the uncommon phenotype

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echocardiogram showing strain imaging assessment

September 10, 2024/Heart, Vascular and Thoracic/Imaging

Mavacamten’s Effects on Strain Imaging in Obstructive HCM: Insights From VALOR-HCM

Serial strain assessments show sustained favorable impacts on LV systolic function and LA function

June 3, 2024/Heart, Vascular and Thoracic/Cardiac Surgery

A Transaortic Approach to Midventricular and Apical Septal Myectomy

Large single-center series demonstrates safety and efficacy for extending procedure

January 22, 2024/Pediatrics/Cardiology

Is Vigorous Exercise in Patients With Hypertrophic Cardiomyopathy Less Risky Than Previously Thought?

JAMA study adds new data to decades-long guidance

HVI_Kelley_4277155_Patient Procedure Shoot- First in Human Trial

October 27, 2023/Genomic Medicine

Cleveland Clinic Treats First Patient With Investigational Gene Therapy for Hypertrophic Cardiomyopathy

One-time infusion of adenovirus-based therapy is designed to restore heart muscle function

August 29, 2023/Heart, Vascular and Thoracic/Research

Updates From CLEAR Outcomes and VALOR-HCM: Expanded Benefits With Bempedoic Acid and Mavacamten

Additional analyses of the two trials presented at 2023 ESC Congress

22-HVI-3509429_obstructive-hypertrophic-cardiomyopathy_650x450

January 27, 2023/Heart, Vascular and Thoracic/Clinical Cardiology

Advances in Hypertrophic Cardiomyopathy Therapy: VALOR-HCM May Be Just the Beginning

An abundance of promising studies are on the horizon

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