Tyrosine kinase inhibitors in the neoadjuvant setting are associated with greater use of partial nephrectomy when treating patients diagnosed with renal masses in a solitary kidney, according to the findings of a new Cleveland Clinic study.
A Cleveland Clinic study finds that race-modified kidney function equations may have contributed to lower use of nephron-sparing surgical approaches in Black patients.
There’s nothing more controversial in the field of localized kidney cancer than decisions about who should get a partial and who should get a radical nephrectomy,” remarks Steven Campbell, MD, PhD, Chair of the AUA Renal Mass Guideline Panel and Vice Chairman of Urology at Cleveland Clinic.
Is there a role for partial nephrectomy in the treatment of metastatic renal cell carcinoma? Cleveland Clinic physicians say improvements in clinical outcomes are enabling novel treatment approaches, including partial nephrectomy, in select patient.
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For most patients with renal masses in a solitary kidney, nephron-sparing approaches are feasible and dialysis is typically unnecessary, a new comprehensive review from Cleveland Clinic finds.
A new study examines the long-term follow-up of patients with stage IV chronic kidney disease who underwent partial nephrectomy. Findings show the potential for more nuanced patient management. Steven C. Campbell, MD, PhD, discusses the data and shares implications for patient care.
Partial nephrectomy has demonstrated positive outcomes over the last decade, becoming the preferred surgical approach for treating renal cancer. But some experts say this may have more to do with selection bias. More clinical studies are needed to better characterize partial nephrectomy versus radical nephrectomy.
Utilizing a rat model of renal ischemia-reperfusion injury, Cleveland Clinic researchers show that mesenchymal stem cell secretions improve recovery of renal function and uncover some aspects of how the secretions produce that beneficial effect.
Cleveland Clinic researchers conducted the most robust study to date on whether measuring contact surface area between the tumor and the normal parenchyma could predict functional outcomes for patient undergoing partial nephrectomy
A Cleveland Clinic study outlines factors associated with optimal preservation of kidney mass and function after partial nephrectomy, with important implications for surgeons.