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Search Results for: psoriasis

May. 3, 2021 / Rheumatology & Immunology / Rheumatic Diseases

Family History of Psoriasis and Acute Psychological Stress Are Associated With the Development of TNFI-Induced Psoriasis

Despite 15 years of experience with tumor necrosis factor -α inhibitor (TNFI) -induced psoriasis, our understanding of its pathogenesis remains incomplete. A recent case-control study identified risk factors and triggers associated with the onset of this condition.

Apr. 23, 2020 / Dermatology & Plastic Surgery

TNFi-Induced Psoriasis and Idiopathic Psoriasis Can Be Distinguished on Biopsy

Is it idiopathic psoriasis or TNFi-induced psoriasis? A new study finds histological differences between these two types of psoriatic lesions that impact treatment.

Jun. 14, 2019 / Rheumatology & Immunology / News & Insights

10 Years of Treating TNF-α Inhibitor-Induced Psoriasis

Comanagement of TNFI-induced psoriasis in rheumatology and dermatology means better patient outcomes, according to a decade of experience at Cleveland Clinic.

Feb. 26, 2019 / Rheumatology & Immunology / Immunologic Diseases

Ustekinumab for Psoriasis in a Patient with HIV-Associated Kaposi Sarcoma

This is the first reported case in which an HIV-positive patient with both severe psoriasis and KS is treated with ustekinumab. The results suggest that the biologic may be a safe and effective treatment for these patients.

Aug. 9, 2017 / Dermatology & Plastic Surgery / News & Insights

How Can Nail Psoriasis Be Best Managed?

How do you sort through all the emerging therapies for nail psoriasis? Dermatologist Thomas J. Knackstedt, MD, advises.

Dec. 22, 2022 / Rheumatology & Immunology / Rheumatic Diseases

Building a Personalized Medicine Approach to PsA Treatment

Cleveland Clinic’s Orthopaedic & Rheumatologic Institute is studying genetic polymorphisms with the aim of improving the understanding of why some individuals do not respond to TNFα blockers. The ultimate goal is to find a new therapeutic approach for those with PsA.

Nov. 23, 2022 / Rheumatology & Immunology / Rheumatic Diseases

When Edema and Dyspnea Accompany Dyschromic Nails

Dyschromic nails, lymphedema and sinus and lung symptoms point to yellow nail syndrome.

Oct. 27, 2022 / Heart, Vascular and Thoracic / Clinical Cardiology

How Autoimmune Disorders Impact Myocardial Infarction Treatment and Long-Term Outcomes

Underlying rheumatic autoimmune disease was associated with reduced use of coronary interventions for MI and a 15% increase in all-cause mortality in the two years after infarction, a large analysis finds.

Sep. 20, 2021 / Rheumatology & Immunology / Arthritis

Advancing the Research on Selective TNF-α Inhibition in Psoriatic Disease

The Husni lab’s ongoing work in TNFR signaling in psoriatic disease has revealed that PRMT5 plays a critical role in TNF-α induction of gene expression at varying levels.

Nov. 6, 2020 / Rheumatology & Immunology / Rheumatic Diseases

Collaborative Rheumatology-Dermatology Clinic Improves Outcomes

Co-management clinics yield improved patient outcomes and increased opportunities for research and education. In this article, rheumatologist Elaine Husni, MD, MPH, and dermatologist Anthony Fernandez, MD, PhD, discuss their new shared clinic.

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